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CD 4+/CD56+ hematodermic neoplasm in infancy: Case report

Title
CD 4+/CD56+ hematodermic neoplasm in infancy: Case report
Authors
Suhng E.A.Cheong S.H.Choi H.Y.Myung K.B.Choi Y.W.
Ewha Authors
명기범최혜영최유원
SCOPUS Author ID
명기범scopusscopus; 최혜영scopus; 최유원scopus
Issue Date
2011
Journal Title
Korean Journal of Dermatology
ISSN
0494-4739JCR Link
Citation
vol. 49, no. 11, pp. 1017 - 1020
Indexed
SCOPUS; KCI scopus
Abstract
CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the World Health ' Organization classification. Several origins of tumor cells have been proposed, but recent studies have shown a relationship with plasmacytoid dendritic cells. A 2-year-old boy presented with multiple bruise-like violaceous subcutaneous nodules and plaques on the trunk, upper and lower extremities. Histological examination showed small-to-medium-sized blastoid cellular infiltration in the dermis and subcutaneous tissue. Tumor cells were positive for CD4, CD56 and TdT, and negative for CD8, CD20 and MPO. It primarily affects elderly patients, but, in this : case, occurred in an infant. Due to its rarity, we present a case of CD4+/CD56+ hematodermic neoplasm affecting a pediatric patient.
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의과대학 > 의학과 > Journal papers
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