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CD 4+/CD56+ hematodermic neoplasm in infancy: Case report
- CD 4+/CD56+ hematodermic neoplasm in infancy: Case report
- Suhng E.A.; Cheong S.H.; Choi H.Y.; Myung K.B.; Choi Y.W.
- Ewha Authors
- 명기범; 최혜영; 최유원
- SCOPUS Author ID
- 명기범; 최혜영; 최유원
- Issue Date
- Journal Title
- Korean Journal of Dermatology
- vol. 49, no. 11, pp. 1017 - 1020
- SCOPUS; KCI
- CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the World Health ' Organization classification. Several origins of tumor cells have been proposed, but recent studies have shown a relationship with plasmacytoid dendritic cells. A 2-year-old boy presented with multiple bruise-like violaceous subcutaneous nodules and plaques on the trunk, upper and lower extremities. Histological examination showed small-to-medium-sized blastoid cellular infiltration in the dermis and subcutaneous tissue. Tumor cells were positive for CD4, CD56 and TdT, and negative for CD8, CD20 and MPO. It primarily affects elderly patients, but, in this : case, occurred in an infant. Due to its rarity, we present a case of CD4+/CD56+ hematodermic neoplasm affecting a pediatric patient.
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