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Expression of Rh glycoproteins in the mammalian kidney

Title
Expression of Rh glycoproteins in the mammalian kidney
Authors
Han K.-H.Kim H.-Y.David Weiner L.
Ewha Authors
한기환
SCOPUS Author ID
한기환scopus
Issue Date
2009
Journal Title
Electrolyte and Blood Pressure
ISSN
1738-5997JCR Link
Citation
vol. 7, no. 1, pp. 14 - 19
Indexed
SCOPUS; KCI scopus
Abstract
Ammonia metabolism is a fundamental process in the maintenance of life in all living organisms. Recent studies have identified ammonia transporter family proteins in yeast (Mep), plants (Amt), and mammals (Rh glycoproteins). In mammalian kidneys, where ammonia metabolism and transport are critically important for the regulation of systemic acid-base homeostasis, basolateral Rh B glycoprotein and apical/basolateral Rh C glycoprotein are expressed along the distal nephron segments. Data from experimental animal models and knockout mice suggest that the Rh glycoproteins appear to mediate important roles in urinary ammonia excretion.
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의과대학 > 의학과 > Journal papers
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