Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 모상준 | * |
dc.date.accessioned | 2016-08-29T12:08:16Z | - |
dc.date.available | 2016-08-29T12:08:16Z | - |
dc.date.issued | 2010 | * |
dc.identifier.issn | 1598-642X | * |
dc.identifier.other | OAK-18103 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/231232 | - |
dc.description.abstract | Undecylprodiginine and streptorubin B are red-pigmented antibiotics produced by Streptomyces coelicolor A3(2). In this study, we investigated the correlation between productivity of these red-pigmented antibiotics and stress of pH shock. Biosynthesis of these red-pigmented antibiotics is enhanced at acidic pH shock on solid R2YE medium. The optimal pH shock is pH 4 which led to 1.6 fold and two-fold increase in the production of undecylprodiginine and streptorubin B as compared with control, respectively. In addition, the extract of pH 4 shocked cells exhibited a remarkable activity against Trichophyton mentagrophytes. However, neutral and basic pH shock did not give raise to promote a production of these red-pigmented antibiotics as well as antifungal activity. Thus, although the acidic pH shock is simple and easy method, it should be extremely effective approach to enhance a productivity of these red-pigmented antibiotics and other secondary metabolites. | * |
dc.language | Korean | * |
dc.title | Enhanced prodiginines production in Streptomyces coelicolor M511 by stress of acidic pH shock | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 38 | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 273 | * |
dc.relation.lastpage | 277 | * |
dc.relation.journaltitle | Korean Journal of Microbiology and Biotechnology | * |
dc.identifier.scopusid | 2-s2.0-77957952258 | * |
dc.author.google | Mo S. | * |
dc.contributor.scopusid | 모상준(23397594700) | * |
dc.date.modifydate | 20240405124155 | * |