View : 32 Download: 0
Serum concentrations of PCBs and OCPs among prepubertal Korean children
- Serum concentrations of PCBs and OCPs among prepubertal Korean children
- Park S.H.; Hong Y.S.; Ha E.-H.; Park H.
- Ewha Authors
- 하은희; 박혜숙; 홍영선
- SCOPUS Author ID
- 하은희; 박혜숙; 홍영선
- Issue Date
- Journal Title
- Environmental Science and Pollution Research
- vol. 23, no. 4, pp. 3536 - 3547
- Biomonitoring; Children; Exposure assessment; Persistent organic pollutants
- Springer Verlag
- SCI; SCIE; SCOPUS
- Although children are more vulnerable than adults to environmental hazards, due to their physiological and behavioral characteristics, few studies have assessed their internal exposure to persistent organic pollutants (POPs). The objective of this study was to determine the serum levels of certain polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) among pre-pubertal children in Korea and examine their variation with age and gender. We analyzed a total of 51 POPs in 214 children (age range, 7–9 years), using data from the Ewha Birth and Growth Cohort Study. To examine change over time, POP concentrations were measured at both 7 and 9 years of age in a sub-cohort of 26 children. The median and interquartile range (IQR, 25th to 75th percentiles) data for the sum of PCB congeners was 26.44 ng/g lipid (18.27–37.63 ng/g lipid). The median (IQR) concentration for the sum of OCPs was 74.82 ng/g lipid (51.11–112.45 ng/g lipid). Our results showed significant increases in serum concentrations of total PCBs with age (p = 0.0001), no gender dependence of total PCBs (p = 0.38) and total OCPs (p = 0.12), and strong correlations between individual POPs. Childhood exposure to POPs was relatively low compared to other studies carried out in different countries. However, even though the use of POPs has been banned since 2001, our results indicated that children in the general population are still exposed to various POPs. Because long-term, low-level exposure to POPs in the general population remains a concern for human health, future research should examine major routes of exposure and identification of risk factors. © 2015, Springer-Verlag Berlin Heidelberg.
- Appears in Collections:
- 의학전문대학원 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- RIS (EndNote)
- XLS (Excel)
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.