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Discrepancies between modified medical research council dyspnea score and COPD assessment test score in patients with COPD
- Title
- Discrepancies between modified medical research council dyspnea score and COPD assessment test score in patients with COPD
- Authors
- Rhee C.K.; Kim J.W.; Hwang Y.I.; Lee J.H.; Jung K.-S.; Lee M.G.; Yoo K.H.; Lee S.H.; Shin K.-C.; Yoon H.K.
- Ewha Authors
- 이진화
- SCOPUS Author ID
- 이진화
- Issue Date
- 2015
- Journal Title
- International Journal of COPD
- ISSN
- 1176-9106
- Citation
- International Journal of COPD vol. 10, no. 1, pp. 1623 - 1631
- Keywords
- CAT; Concordance; COPD; Discrepancy; mMRC
- Publisher
- Dove Medical Press Ltd.
- Indexed
- SCOPUS
- Document Type
- Article
- Abstract
- Background and objective: According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, either a modified Medical Research Council (mMRC) dyspnea score of ≥2 or a chronic obstructive pulmonary disease (COPD) assessment test (CAT) score of ≥10 is considered to represent COPD patients who are more symptomatic. We aimed to identify the ideal CAT score that exhibits minimal discrepancy with the mMRC score. Methods: A receiver operating characteristic curve of the CAT score was generated for an mMRC scores of 1 and 2. A concordance analysis was applied to quantify the association between the frequencies of patients categorized into GOLD groups A–D using symptom cutoff points. A κ-coefficient was calculated. Results: For an mMRC score of 2, a CAT score of 15 showed the maximum value of Youden’s index with a sensitivity and specificity of 0.70 and 0.66, respectively (area under the receiver operating characteristic curve [AUC] 0.74; 95% confidence interval [CI], 0.70–0.77). For an mMRC score of 1, a CAT score of 10 showed the maximum value of Youden’s index with a sensitivity and specificity of 0.77 and 0.65, respectively (AUC 0.77; 95% CI, 0.72–0.83). The κ value for concordance was highest between an mMRC score of 1 and a CAT score of 10 (0.66), followed by an mMRC score of 2 and a CAT score of 15 (0.56), an mMRC score of 2 and a CAT score of 10 (0.47), and an mMRC score of 1 and a CAT score of 15 (0.43). Conclusion: A CAT score of 10 was most concordant with an mMRC score of 1 when classifying patients with COPD into GOLD groups A–D. However, a discrepancy remains between the CAT and mMRC scoring systems. © 2015 Rhee et al.
- DOI
- 10.2147/COPD.S87147
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
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