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Discrepancies between modified medical research council dyspnea score and COPD assessment test score in patients with COPD

Title
Discrepancies between modified medical research council dyspnea score and COPD assessment test score in patients with COPD
Authors
Rhee C.K.Kim J.W.Hwang Y.I.Lee J.H.Jung K.-S.Lee M.G.Yoo K.H.Lee S.H.Shin K.-C.Yoon H.K.
Ewha Authors
이진화
SCOPUS Author ID
이진화scopus
Issue Date
2015
Journal Title
International Journal of COPD
ISSN
1176-9106JCR Link
Citation
vol. 10, no. 1, pp. 1623 - 1631
Keywords
CATConcordanceCOPDDiscrepancymMRC
Publisher
Dove Medical Press Ltd.
Indexed
SCOPUS WOS scopus
Abstract
Background and objective: According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, either a modified Medical Research Council (mMRC) dyspnea score of ≥2 or a chronic obstructive pulmonary disease (COPD) assessment test (CAT) score of ≥10 is considered to represent COPD patients who are more symptomatic. We aimed to identify the ideal CAT score that exhibits minimal discrepancy with the mMRC score. Methods: A receiver operating characteristic curve of the CAT score was generated for an mMRC scores of 1 and 2. A concordance analysis was applied to quantify the association between the frequencies of patients categorized into GOLD groups A–D using symptom cutoff points. A κ-coefficient was calculated. Results: For an mMRC score of 2, a CAT score of 15 showed the maximum value of Youden’s index with a sensitivity and specificity of 0.70 and 0.66, respectively (area under the receiver operating characteristic curve [AUC] 0.74; 95% confidence interval [CI], 0.70–0.77). For an mMRC score of 1, a CAT score of 10 showed the maximum value of Youden’s index with a sensitivity and specificity of 0.77 and 0.65, respectively (AUC 0.77; 95% CI, 0.72–0.83). The κ value for concordance was highest between an mMRC score of 1 and a CAT score of 10 (0.66), followed by an mMRC score of 2 and a CAT score of 15 (0.56), an mMRC score of 2 and a CAT score of 10 (0.47), and an mMRC score of 1 and a CAT score of 15 (0.43). Conclusion: A CAT score of 10 was most concordant with an mMRC score of 1 when classifying patients with COPD into GOLD groups A–D. However, a discrepancy remains between the CAT and mMRC scoring systems. © 2015 Rhee et al.
DOI
10.2147/COPD.S87147
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의학전문대학원 > 의학과 > Journal papers
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