Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 박경란 | - |
dc.date.accessioned | 2016-08-29T12:08:18Z | - |
dc.date.available | 2016-08-29T12:08:18Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2234-1900 | - |
dc.identifier.other | OAK-15269 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/230692 | - |
dc.description.abstract | Purpose: We evaluated the prognostic significance of T3 subtypes and the role of adjuvant radiotherapy in patients with resected the American Joint Committee on Cancer stage IIB T3N0M0 non-small cell lung cancer (NSCLC). Materials and Methods: T3N0 NSCLC patients who underwent resection from January 1990 to October 2009 (n = 102) were enrolled and categorized into 6 subgroups according to the extent of invasion: parietal pleura chest wall invasion, mediastinal pleural invasion, diaphragm invasion, separated tumor nodules in the same lobe, endobronchial tumor <2 cm distal to the carina, and tumor-associated collapse. Results: The median overall survival (OS) and disease-free survival (DFS) were 55.3 months and 51.2 months, respectively. In postoperative T3N0M0 patients, the tumor size was a significant prognostic factor for survival (OS, p = 0.035 and DFS, p = 0.035, respectively). Patients with endobronchial tumors within 2 cm of the carina also showed better OS and DFS than those in the other T3 subtypes (p = 0.018 and p = 0.016, respectively). However, adjuvant radiotherapy did not cause any improvement in survival (OS, p = 0.518 and DFS, p = 0.463, respectively). Only patients with mediastinal pleural invasion (n = 25) demonstrated improved OS and DFS after adjuvant radiotherapy (n = 18) (p = 0.012 and p = 0.040, respectively). Conclusion: The T3N0 NSCLC subtype that showed the most favorable prognosis is the one with endobronchial tumors within 2 cm of the carina. Adjuvant radiotherapy is not effective in improving survival outcome in resected T3N0 NSCLC. © 2015. The Korean Society for Radiation Oncology. | - |
dc.language | English | - |
dc.publisher | Department of Radiation Oncology | - |
dc.subject | Adjuvant radiotherapy | - |
dc.subject | Non-small cell lung cancer | - |
dc.subject | Prognostic factor | - |
dc.title | Multi-institutional analysis of T3 subtypes and adjuvant radiotherapy effects in resected T3N0 non-small cell lung cancer patients | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 33 | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 75 | - |
dc.relation.lastpage | 82 | - |
dc.relation.journaltitle | Radiation Oncology Journal | - |
dc.identifier.doi | 10.3857/roj.2015.33.2.75 | - |
dc.identifier.scopusid | 2-s2.0-84936749249 | - |
dc.author.google | Choi Y. | - |
dc.author.google | Lee I.J. | - |
dc.author.google | Lee C.Y. | - |
dc.author.google | Cho J.H. | - |
dc.author.google | Choi W.H. | - |
dc.author.google | Yoon H.I. | - |
dc.author.google | Lee Y.-H. | - |
dc.author.google | Lee C.G. | - |
dc.author.google | Keum K.C. | - |
dc.author.google | Chung K.Y. | - |
dc.author.google | Haam S.J. | - |
dc.author.google | Paik H.C. | - |
dc.author.google | Lee K.K. | - |
dc.author.google | Moon S.R. | - |
dc.author.google | Lee J.-Y. | - |
dc.author.google | Park K.-R. | - |
dc.author.google | Kim Y.S. | - |
dc.contributor.scopusid | 박경란(14040340300;57203047823;57207108839;57308917900) | - |
dc.date.modifydate | 20230118120244 | - |