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Bio-layered double hydroxides nanohybrids for theranostics applications

Title
Bio-layered double hydroxides nanohybrids for theranostics applications
Authors
Park D.-H.Choi G.Choy J.-H.
Ewha Authors
최진호
SCOPUS Author ID
최진호scopus
Issue Date
2015
Journal Title
Structure and Bonding
ISSN
0081-5993JCR Link
Citation
vol. 166, pp. 137 - 175
Keywords
Bio-LDHBiomedicalDiagnosisDrug delivery systemGene delivery systemImagingLayered double hydroxide (LDH)NanohybridNanomedicineTargetingTheranosticsTherapy
Publisher
Springer Verlag
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
Bio-related science has been one of the most important fields in the viewpoint of health and welfare of human being. A biofunctionalization of inorganic nanoparticles becomes more and more important in the near future, since it allows what is called theranostics, a new concept of next-generation medicine that combines therapeutics and diagnosis. Ever since the notion of intercalative bioinorganic nanohybrids was created based on the layered double hydroxide (LDH) material, a variety of bio-LDH nanohybrids have been developed to provide new opportunities toward theranostic biomedical applications. In this chapter, we review the structural chemistry of several bio-LDH nanohybrids available for gene and drug delivery system and focus on the platform strategies for advanced theranostic system. The cellular trafficking mechanism of LDH and cancer therapeutic efficacy along with diagnostic imaging of the bio-LDH nanohybrids are also discussed in in vitro as well as in vivo studies. © 2015 Springer International Publishing Switzerland.
DOI
10.1007/978-3-319-16991-0-4
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자연과학대학 > 화학·나노과학전공 > Journal papers
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