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Near-infrared light-responsive nanomaterials for cancer theranostics

Title
Near-infrared light-responsive nanomaterials for cancer theranostics
Authors
Kim H.Chung K.Lee S.Kim D.H.Lee H.
Ewha Authors
이승진김동하김희정이혁진
SCOPUS Author ID
이승진scopus; 김동하scopus; 김희정scopusscopusscopus; 이혁진scopus
Issue Date
2016
Journal Title
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
ISSN
1939-5116JCR Link
Citation
vol. 8, no. 1, pp. 23 - 45
Publisher
Wiley-Blackwell
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Early diagnosis and effective cancer therapy are required, to properly treat cancer, which causes more than 8.2 million deaths in a year worldwide. Among various cancer treatments, nanoparticle-based cancer therapies and molecular imaging techniques have been widely exploited over the past decades to overcome current drawbacks of existing cancer treatments. In particular, gold nanoparticles (AuNPs), carbon nanotubes (CNTs), graphene oxide (GO), and upconversion nanocrystals (UNCs) have attracted tremendous attention from researchers due to their near-infrared (NIR) light-responsive behaviors. These nanomaterials are considered new multifunctional platforms for cancer theranostics. They would enable on-demand control of drug release or molecular imaging in response to a remote trigger by NIR light exposure. This approach allows the patient or physician to adjust therapy precisely to a target site, thus greatly improving the efficacy of cancer treatments, while reducing undesirable side effects. In this review, we have summarized the advantages of NIR light-responsive nanomaterials for in vivo cancer treatments, which includes NIR triggered photothermal therapy (PTT) and photodynamic therapy (PDT). Furthermore, recent developments, perspectives, and new challenges of NIR light-responsive nanomaterials are discussed for cancer theranostic applications. © 2016 Wiley Periodicals, Inc.
DOI
10.1002/wnan.1347
Appears in Collections:
약학대학 > 약학과 > Journal papers
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