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Cognitive and behavioral abnormalities of vascular dementia

Title
Cognitive and behavioral abnormalities of vascular dementia
Authors
Jeong J.H.Kim E.-J.Seo S.W.Na D.L.
Ewha Authors
정지향
SCOPUS Author ID
정지향scopus
Issue Date
2009
Journal Title
The Behavioral Neurology of Dementia
Publisher
Cambridge University Press
Indexed
SCOPUS scopus
Abstract
Introduction Vascular dementia (VaD) is a cognitive syndrome caused by cerebrovascular disease with clinically apparent ischemic or hemorrhagic lesions. It is not synonymous with post-stroke dementia, which refers to any type of dementia developed after a clinical stroke, irrespective of the presumed cause for the dementia (Pasquier et al.,1997). Unlike Alzheimer's disease (AD), which is accepted as the most common cause of dementia, reports on VaD show remarkably variable prevalence. Compared with western countries, the prevalence of VaD seems somewhat higher in eastern Asian countries such as China, South Korea and Japan, ranking second (Lee et al., 2002; Zhang et al., 2005; Dong et al., 2007) or even approaching the prevalence of AD (Yanagihara 2002). As the occurrence of stroke rises exponentially with age, the contribution of vascular disease to the incidence, pathogenesis and clinical course of dementia is becoming more important in the elderly. Also, the incidence of AD doubles in stroke patients, confounding understanding of the relative contribution of the two conditions to clinical status and treatment (Kokmen et al., 1996). Importantly, cognitive decline after stroke is common. In patients with a first stroke, fully one-fourth develop a newly diagnosed dementia within 1 year after the event (Andersen et al., 1996). Similarly, the relative risk of new onset of dementia is 5.5 within 4 years after first ever stroke (Tatemichi et al., 1994). The clinical patterns of VaD differ, depending on the vessels involved (large versus small vessel), location of vascular lesions and the stages of disease. © Cambridge University Press 2009.
DOI
10.1017/CBO9780511581410.021
ISBN
9780511581410; 9780521853958
Appears in Collections:
의과대학 > 의학과 > Journal papers
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