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Seasonality of gout in Korea: A multicenter study

Title
Seasonality of gout in Korea: A multicenter study
Authors
Choi H.J.Lee C.H.Lee J.H.Yoon B.Y.Kim H.A.Suh C.H.Choi S.T.Song J.S.Joo H.Choi S.J.Lee J.S.Shin K.Jun J.-B.Baek H.J.
Ewha Authors
이지수
SCOPUS Author ID
이지수scopus
Issue Date
2015
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934JCR Link
Citation
vol. 30, no. 3, pp. 240 - 244
Keywords
FlaresGout onsetKoreaSeasonalitySummer
Publisher
Korean Academy of Medical Science
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
The object of this study was to evaluate the seasonality of gout in Korea. We retrospectively examined data from 330 patients seen at nine rheumatology clinics, treated with urate lowering therapy (ULT) more than one year after stopping prophylactic medication. Demographic data, clinical and laboratory features, and seasonality of gout onset and flares were collected. Season was classified in three-month intervals. The mean age was 52.2 yr and mean disease duration was 26.8 months. The male to female count was 318:12. The onset of acute gouty attacks was obtained in 256 patients. Gout developed most commonly in summer season (36.7%) (P < 0.001) and in June (15.6%, P = 0.002). During ULT, there were 147 (male 97.3%) gout flares. Although there was no statistically significant difference, gout flares were more common in summer (30.6%). Aggravating factors were identified in 57 flares: alcohol (72.0%) was most common. In the patients who attained target serum uric acid (< 6 mg/dL) at the end of prophylaxis, gout flares were high in fall (35.8%) and September (17.0%). In Korea, the summer is most common season of gout onset and there is a tendency for gout flares to increase during ULT in summer/fall season. © 2015 The Korean Academy of Medical Sciences.
DOI
10.3346/jkms.2015.30.3.240
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의학전문대학원 > 의학과 > Journal papers
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