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dc.contributor.author류동열-
dc.date.accessioned2016-08-29T12:08:54Z-
dc.date.available2016-08-29T12:08:54Z-
dc.date.issued2015-
dc.identifier.issn0025-7974-
dc.identifier.otherOAK-14651-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/230467-
dc.description.abstractVitamin D deficiency is frequently found in patients with renal transplants (RTxs). Because vitamin D plays indispensable roles in the immune system, there may be an association between vitamin D deficiency and infection in these patients, but this has not been fully elucidated. Therefore, this study investigated the impact of pre-RTx vitamin D deficiency on urinary tract infection (UTI) development after RTx. We measured 25-hydroxyvitamin D3 (25(OH)D3) levels in 410 patients 2 weeks before they underwent RTx. Vitamin D deficiency was defined as 25(OH)D3 <10ng/mL. The primary outcome was UTI occurrence after RTx. Cox proportional hazard analysis determined whether vitamin D deficiency was independently associated with UTI. The mean 25(OH)D3 level was 12.8±6.9ng/mL, and 171 patients (41.7%) were vitamin D deficient. During a median follow-up duration of 7.3 years, the UTI incidence was significantly higher in vitamin D-deficient patients (52 patients, 30.4%) compared with vitamin D-nondeficient patients (40 patients, 16.7%) (P=0.001). Moreover, multivariate Cox proportional hazard analysis showed that vitamin D deficiency was an independent predictor of UTI after RTx (hazard ratio 1.81, 95% confidence interval 1.11-2.97, P=0.02). Vitamin D deficiency was an independent risk factor for UTI after RTx; hence, determining 25(OH)D3 levels might help to predict infectious complications after RTx. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.-
dc.languageEnglish-
dc.publisherLippincott Williams and Wilkins-
dc.titleVitamin D deficiency is an independent risk factor for urinary tract infections after renal transplants-
dc.typeArticle-
dc.relation.issue9-
dc.relation.volume94-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpagee594-
dc.relation.journaltitleMedicine (United States)-
dc.identifier.doi10.1097/MD.0000000000000594-
dc.identifier.wosidWOS:000350756800015-
dc.identifier.scopusid2-s2.0-84926334222-
dc.author.googleKwon Y.E.-
dc.author.googleKim H.-
dc.author.googleOh H.J.-
dc.author.googlePark J.T.-
dc.author.googleHan S.H.-
dc.author.googleRyu D.-R.-
dc.author.googleYoo T.-H.-
dc.author.googleKang S.-W.-
dc.contributor.scopusid류동열(7103144218)-
dc.date.modifydate20180329113130-
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