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Performance IQ in children is associated with blood cadmium concentration in early pregnancy

Title
Performance IQ in children is associated with blood cadmium concentration in early pregnancy
Authors
Jeong K.S.Park H.Ha E.Hong Y.-C.Ha M.Kim B.-N.Lee B.-E.Lee S.-J.Lee K.Y.Kim J.H.Kim Y.
Ewha Authors
하은희박혜숙
SCOPUS Author ID
하은희scopus; 박혜숙scopus
Issue Date
2015
Journal Title
Journal of Trace Elements in Medicine and Biology
ISSN
0946-672XJCR Link
Citation
vol. 30, pp. 107 - 111
Keywords
Blood cadmiumIQPerformanceWPPSI-R
Publisher
Elsevier GmbH
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Objective: To investigate whether performance IQ in children is associated with maternal blood cadmium concentration in early pregnancy. Method: The present study is a component of the Mothers' and Children's Environmental Health (MOCEH) study, a multi-center birth cohort project in Korea that began in 2006. The study cohort consisted of 119 children whose mothers underwent testing of blood cadmium during early pregnancy. All children were evaluated using the Korean version of the Wechsler Preschool and Primary Scale of Intelligence, revised edition (WPPSI-R), at 60 months of age. Multivariate linear regression analysis was performed to analyze the correlation between IQ in children and maternal blood cadmium concentration in early pregnancy, after adjustment for covariates. Results: Maternal blood cadmium concentration during early pregnancy was inversely associated with performance IQ, after adjustment for covariates such as sex, educational levels of both parents, family income, and maternal BMI. Maternal blood cadmium concentration, however, was not associated with cognitive IQ. Conclusion: Performance IQ in children is associated with maternal blood cadmium concentration in early pregnancy. © 2014 Elsevier GmbH.
DOI
10.1016/j.jtemb.2014.11.007
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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