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The Clinical meaning of Benign colon uptake in 18F-FDG PET: Comparison with colonoscopic findings

Title
The Clinical meaning of Benign colon uptake in 18F-FDG PET: Comparison with colonoscopic findings
Authors
Roh S.H.Jung S.-A.Kim S.-E.Kim H.-I.Jin Lee M.Hyun Tae C.Young Choi J.Shim K.-N.Jung H.-K.Hun Kim T.Yoo K.Moon H.Sahn Kim B.
Ewha Authors
문일환유권정성애정혜경심기남김성은김범산
SCOPUS Author ID
문일환scopus; 유권scopus; 정성애scopus; 정혜경scopus; 심기남scopus; 김성은scopus; 김범산scopus
Issue Date
2012
Journal Title
Clinical Endoscopy
ISSN
2234-2400JCR Link
Citation
vol. 45, no. 2, pp. 145 - 150
Indexed
SCOPUS; KCI scopus
Abstract
Background/Aims: Benign colon 18F-fluorodeoxyglucose (FDG) uptake is frequently observed in asymptomatic individuals. Aims of this study were to investigate the benign colon uptake by whole body FDG-positron emission tomography (PET) in asymptomatic adults and to correlate those results with colonoscopic and histologic findings. Methods: Among 3,540 subjects who had undergone FDG-PET, 43 subjects who were diagnosed to have benign colon uptake in FDG-PET and underwent colonoscopy were retrospectively reviewed. Subjects were classified as diffuse or focal groups based on their FDG uptake patterns. PET results were analyzed together with colonoscopic and histologic findings. Results: Forty-three subjects showed benign colon uptake in FDG-PET; 28 of them were shown as the diffuse group, while other 15 subjects were classified as the focal group. Five subjects among those showed diffuse uptake were diagnosed as adenoma. Seven among 15 subjects who showed focal uptake were diagnosed as adenocarcinoma (n=2), adenoma (n=3), or non-neoplastic polyp (n=2). Positive predictive values were 25% in the diffuse group and 47% in the focal group. Conclusions: We recommend that patients showing benign FDG uptake in the colon should be further evaluated by colonoscopy, especially for patients with focal FDG uptake. © 2012 Korean Society of Gastrointestinal Endoscopy.
DOI
10.5946/ce.2012.45.2.145
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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