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Mycoplasma pneumoniae infection in patients with Kawasaki disease

Title
Mycoplasma pneumoniae infection in patients with Kawasaki disease
Authors
Lee M.N.Cha J.H.Ahn H.M.Yoo J.H.Kim H.S.Sohn S.Hong Y.M.
Ewha Authors
홍영미유정현김혜순손세정
SCOPUS Author ID
홍영미scopus; 유정현scopus; 김혜순scopus; 손세정scopus
Issue Date
2011
Journal Title
Korean Journal of Pediatrics
ISSN
1783-1061JCR Link
Citation
vol. 54, no. 3, pp. 122 - 126
Indexed
SCOPUS scopus
Abstract
Purpose: Kawasaki disease (KD) is the main cause of acquired heart disease in children. In addition to cardiovascular involvement, many complications have been recognized in KD. However, respiratory complications have been rarely reported. We investigated the differences in clinical characteristics, laboratory findings, radiography findings, and echocardiography findings of Mycoplasma pneumoniae infection and other types of pneumonia in KD patients. Methods: Among 358 patients with KD, 54 developed concurrent pneumonia. Among the 54 patients, 12 (22.2%) with high titers of anti-M. pneumoniae antibody (AMA) (>1:640) were grouped in the M. pneumoniae group and 42 were included in the control group. Serum AMA was measured in each patient. Clinical laboratory findings and total duration of fever were analyzed. Results: The duration of fever, serum hemoglobin, white blood cell count, platelet count, erythrocyte sedimentation rate, C-reactive protein level, albumin level, and the incidence of coronary arterial lesions showed no statistical difference in the 2 groups. Neutrophil count was significantly higher in the M. pneumoniae group than in the control group. Among various radiography findings observed in pneumonia, consolidation and pleural effusion were more frequent in the M. pneumoniae group than in the control group. On the other hand, parahilar peribronchial opacification, diffuse interstitial lesion, and normal findings prevailed in the control group. Conclusion: KD patients can have concurrent infections, especially pulmonary symptoms. The cause of KD is likely to be associated with M. pneumoniae infection. Thus, immediate treatment of M. pneumoniae infection in KD patients is very important. © 2011 by The Korean Pediatric Society.
DOI
10.3345/kjp.2011.54.3.122
Appears in Collections:
의과대학 > 의학과 > Journal papers
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