Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이동현 | * |
dc.contributor.author | 윤하나 | * |
dc.date.accessioned | 2016-08-28T11:08:12Z | - |
dc.date.available | 2016-08-28T11:08:12Z | - |
dc.date.issued | 2010 | * |
dc.identifier.issn | 2005-6737 | * |
dc.identifier.other | OAK-13379 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/229385 | - |
dc.description.abstract | Purpose: We examined the effect of stress on the pathophysiology of bladder stability in terms of enzyme levels, Rho-kinase, and bladder relaxation. Materials and Methods: A total of 48 female Sprague-Dawley rats were studied in scheduled stress environments for 7, 14, and 28 days; 24 rats were in the control group and 24 rats were in the test (stressed) group. Results: Estrogen decreased significantly whereas testosterone and dopamine increased significantly in the stress group (p<0.05). Rho-kinase was significantly increased in the rats exposed to stress stimuli for 14 days (p<0.05). Collagen types I and III in the bladder tissue were significantly higher in rats exposed to stress for 14 days and 28 days (collagen type I in the 14-day group, p<0.01; collagen type I in the 28-day group, p<0.05; collagen type III in the 14-day and 28-day groups, p<0.05). Voiding frequency increased significantly as the duration of stress exposure was prolonged, in addition to a significant decrease in volume per voiding (p<0.05). Conclusions: The changes observed in micturition pattern, factors that contribute to smooth muscle contraction, and relaxation in the female rat bladder support the hypothesis that stress affects bladder stability. © The Korean Urological Association, 2010. | * |
dc.language | English | * |
dc.title | Effect of stress on the expression of Rho-kinase and collagen in rat bladder tissue | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 51 | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 132 | * |
dc.relation.lastpage | 138 | * |
dc.relation.journaltitle | Korean Journal of Urology | * |
dc.identifier.doi | 10.4111/kju.2010.51.2.132 | * |
dc.identifier.scopusid | 2-s2.0-77149175625 | * |
dc.author.google | Yoon H. | * |
dc.author.google | Lee D. | * |
dc.author.google | Chun K. | * |
dc.author.google | Yoo J. | * |
dc.contributor.scopusid | 이동현(24341048900;57202299352) | * |
dc.contributor.scopusid | 윤하나(8723844200) | * |
dc.date.modifydate | 20240118161124 | * |