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Infectious mononucleosis hepatitis in young adults: Two case reports

Title
Infectious mononucleosis hepatitis in young adults: Two case reports
Authors
Kang M.-J.Kim T.-H.Shim K.-N.Jung S.-A.Cho M.-S.Yoo K.Chung K.W.
Ewha Authors
유권정성애조민선심기남김태헌
SCOPUS Author ID
유권scopus; 정성애scopus; 조민선scopus; 심기남scopus; 김태헌scopus
Issue Date
2009
Journal Title
Korean Journal of Internal Medicine
ISSN
1226-3303JCR Link
Citation
vol. 24, no. 4, pp. 381 - 387
Indexed
SCIE; SCOPUS; KCI scopus
Abstract
Infectious mononucleosis due to Epstein-Barr virus (EBV) infection sometimes causes acute hepatitis, which is usually self-limiting with mildly elevated transaminases, but rarely with jaundice. Primary EBV infection in children is usually asymptomatic, but in a small number of healthy individuals, typically young adults, EBV infection results in a clinical syndrome of infectious mononucleosis with hepatitis, with typical symptoms of fever, pharyngitis, lymphadenopathy, and hepatosplenomegaly. EBV is rather uncommonly confirmed as an etiologic agent of acute hepatitis in adults. Here, we report two cases: the first case with acute hepatitis secondary to infectious mononucleosis and a second case, with acute hepatitis secondary to infectious mononucleosis concomitantly infected with hepatitis A. Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy and electron microscopic study.
DOI
10.3904/kjim.2009.24.4.381
Appears in Collections:
의과대학 > 의학과 > Journal papers
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