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Perinatal changes in size of the fetal great arteries

Title
Perinatal changes in size of the fetal great arteries
Authors
Hae S.K.Young M.H.Sejung S.Jung Y.C.
Ewha Authors
홍영미김혜순손세정
SCOPUS Author ID
홍영미scopus; 김혜순scopus; 손세정scopus
Issue Date
2009
Journal Title
Korean Circulation Journal
ISSN
1738-5520JCR Link
Citation
vol. 39, no. 10, pp. 414 - 417
Indexed
SCIE; SCOPUS; KCI scopus
Abstract
Background and Objectives: At birth, the fetal circulation must immediately adapt to extrauterine life. Our goal was to evaluate perinatal changes in the size of the aorta (Ao) and pulmonary artery (PA), and to investigate factors influencing these changes. Subjects and Methods: Aortic and PA diameters were measured by echocardiography in 50 healthy term babies one day before and 4 to 5 days after birth. Results: Compared with prenatal measurements, the Ao increased (from 7.4±0.6 mm to 8.4±0.6 mm, p<0.01) and the PA decreased (from 9.5 ±0.8 mm to 8.7±0.8 mm, p<0.01) in size after birth. The Ao/PA ratio increased from 0.78±0.07 before birth to 0.97±0.08 after birth (p<0.01), but there was no significant difference in the sum of the diameters of the great arteries between pre- and postnatal measurements. Postnatal increases in aortic size correlated negatively with prenatal aortic diameter (r=-0.37, p<0.05), but was not related to body weight. According to multiple regression analysis, significant variables for predicting perinatal changes in size of the Ao and PA were the prenatal Ao/PA ratio and the prenatal PA diameter, respectively. Conclusion: Despite a difference existing in prenatal diameters between Ao and PA, circulatory changes at birth make the great artery sizes equal, and do so regardless of body weight. Copyright © 2009 The Korean Society of Cardiology.
DOI
10.4070/kcj.2009.39.10.414
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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