Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오세관 | * |
dc.date.accessioned | 2016-08-28T11:08:02Z | - |
dc.date.available | 2016-08-28T11:08:02Z | - |
dc.date.issued | 2008 | * |
dc.identifier.issn | 1976-9148 | * |
dc.identifier.other | OAK-13272 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/229291 | - |
dc.description.abstract | Apoptosis is essential for a variety of pathophysiological progress. Apoptosis induction by various agents changes cellular morphology, DNA content and lipid membrane composition. Recently, sphingosine 1-phosphate (S1P) is avidly released from not only platelets and erythrocytes but vascular endothelium. Here we established S1P releasing cells by deleting S1P lyase (F9-12 cells). We observed apoptosis induction by the treatment of fumonisin B1 (FB1) in F9-12 cells but not in F9 wild-type cells. We measured high amounts of accumulated S1P and dihydroS1P (DHS1P) in FB1-induced apoptotic F9-12 cells. We also showed DHS1P release in an early stage of the apoptosis induction by FB1 but not by phorbol 12-myristate 13-acetate (PMA)-induced apoptosis, suggesting differential apoptotic processes. | * |
dc.language | English | * |
dc.title | Fumonisin B1 induces apoptosis in sphingosine 1-phosphate lyase-null F9 cells through increase of sphingolipids levels | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 16 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 95 | * |
dc.relation.lastpage | 99 | * |
dc.relation.journaltitle | Biomolecules and Therapeutics | * |
dc.identifier.doi | 10.4062/biomolther.2008.16.2.095 | * |
dc.identifier.wosid | WOS:000257695700005 | * |
dc.identifier.scopusid | 2-s2.0-69549116568 | * |
dc.author.google | Pak S.-M. | * |
dc.author.google | Park N.-Y. | * |
dc.author.google | Park M.-Y. | * |
dc.author.google | Kim W.-J. | * |
dc.author.google | Lee J.-H. | * |
dc.author.google | Oh S. | * |
dc.author.google | Yoo H.-S. | * |
dc.author.google | Lee Y.-M. | * |
dc.contributor.scopusid | 오세관(7404103757) | * |
dc.date.modifydate | 20240118133340 | * |