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Comparison of sirolimus-eluting stent and paclitaxel-eluting stent for long-term cardiac adverse events in diabetic patients: The Korean multicenter angioplasty team (KOMATE) registry

Title
Comparison of sirolimus-eluting stent and paclitaxel-eluting stent for long-term cardiac adverse events in diabetic patients: The Korean multicenter angioplasty team (KOMATE) registry
Authors
Kim J.-S.Lee B.H.Ko Y.-G.Choi D.Jang Y.Min P.-K.Yoon Y.-W.Hong B.K.Kwon H.M.Ahn M.-S.Lee S.-H.Yoon J.H.Lee B.K.Kim B.O.Kim B.-K.Oh S.J.Jeon D.W.Yang J.Y.Cho J.R.Jung J.-H.Ryu S.-K.Kwon K.Park S.H.Byun Y.S.Ko C.W.
Ewha Authors
권기환
SCOPUS Author ID
권기환scopus
Issue Date
2008
Journal Title
Catheterization and Cardiovascular Interventions
ISSN
1522-1946JCR Link
Citation
vol. 72, no. 5, pp. 601 - 607
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
Background: There is some controversy on long-term cardiac outcomes between sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in diabetes mellitus (DM). We compared cardiac adverse events after SES and PES implantation in patients with DM over a period of 3 year. Methods: A total of 634 patients with DM treated with SES (n 5 428) or PES (n 5 206) were consecutively enrolled in the KOMATE registry from 2003 to 2004. We assessed major adverse cardiac events (MACEs, cardiovascular death, non-fatal myocardial infarction, ischemia driven target vessel revascularization) and stent thrombosis (ST) according to the definitions set by the Academic Research Consortium. Results: Propensity score (PS) analysis was performed to adjust different baseline characteristics. The mean follow-up duration was 38 ± 8 month (at least 36 month and up to 53 month). The 3-year MACE rate did not show a significant difference between the two groups [52 (12.1%) in SES vs. 29 (14.1%) in PES, P = 0.496]. The definite and probable ST at 3 year were similar in both SES and PES [12 (2.8%) in SES vs. 7 (3.4%) in PES, P = 0.681]. There were no differences in hazard ratio for MACE and ST between two stents [MACE, crude: 0.844 (0.536-1.330) and adjusted for PS: 0.858 (0.530-1.389); ST, crude: 0.820 (0.323-2.083) and adjusted for PS: 0.960 (0.357-2.587)]. Conclusions: The present study demonstrated that long-tem cardiac outcomes including ST were not significantly different between SES and PES in patients with DM. © 2008 Wiley-Liss, Inc.
DOI
10.1002/ccd.21700
Appears in Collections:
의과대학 > 의학과 > Journal papers
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