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Feminization and reduction of testicular weight in mouse sparganosis.

Title
Feminization and reduction of testicular weight in mouse sparganosis.
Authors
Yang H.J.
Ewha Authors
양현종
SCOPUS Author ID
양현종scopus
Issue Date
2006
Journal Title
The Korean journal of parasitology
ISSN
0023-4001JCR Link
Citation
vol. 44, no. 2, pp. 167 - 169
Indexed
SCIE; SCOPUS; KCI scopus
Abstract
After infection of male mice with the plerocercoids (spargana) of Spirometra mansoni, serum levels of estrogen and testicular weight were analyzed by enzyme-linked immunosorbent assay (ELISA) and weighing machine, respectively. The serum level of estrogen increased progressively in infected mice compared with normal controls, whereas the testicular weight of infected mice decreased significantly (P < 0.05). These results suggest that certain substances from spargana change the steroid hormone metabolisms in the host by unknown pathways, and chronic infection may contribute to change of the function of steroid hormone target organ, i.e., testis, in male mice.
DOI
10.3347/kjp.2006.44.2.167
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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