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Prevalence and factor analysis of metabolic syndrome in an urban Korean population

Title
Prevalence and factor analysis of metabolic syndrome in an urban Korean population
Authors
Oh J.-Y.Hong Y.S.Sung Y.-A.Barrett-Connor E.
Ewha Authors
성연아홍영선오지영
SCOPUS Author ID
성연아scopus; 홍영선scopus; 오지영scopus
Issue Date
2004
Journal Title
Diabetes Care
ISSN
0149-5992JCR Link
Citation
vol. 27, no. 8, pp. 2027 - 2032
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
OBJECTIVE - The aim of this study was to explore the prevalence and pattern of the metabolic syndrome and its association with hyperinsulinemia in an urban Korean population of 269 men and 505 women. RESEARCH DESIGN AND METHODS - The National Cholesterol Education Program Adult Treatment Panel (ATP) III guidelines were used to calculate the sex-specific prevalence of the metabolic syndrome. After excluding individuals taking medication for hypertension, diabetes, or dyslipidemia, we used factor analysis to examine the pattern of the metabolic syndrome in 206 men and 449 women. RESULTS - The prevalence of metabolic syndrome was 16.0% in men and 10.7% in women aged 30-80 years. However, ATP III criteria for central obesity are not optimal for an Asian-Pacific population; when waist circumference is reduced from 102 to 90 cm in men and 88 to 80 cm in women, the prevalence of the metabolic syndrome increased to 29.0 and 16.8%, respectively. Sex-specific factor analysis showed four factors in men (obesity, glucose intolerance, hypertension, and dyslipidemia) and three in women (obesity-hypertension, glucose intolerance, and obesity-dyslipidemia). Insulin resistance estimated from fasting insulin levels clustered with three of the four factors in men and two of the three factors in women. By ATP III or Asian-Pacific waist circumference criteria, the prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance, which was estimated by a homeostasis model assessment. CONCLUSIONS - The metabolic syndrome is common in an urban Korean population when using Asian-Pacific waist criteria. The prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance.
DOI
10.2337/diacare.27.8.2027
Appears in Collections:
의과대학 > 의학과 > Journal papers
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