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Electrospun poly (lactic-co-glycolic acid)(PLGA) microparticles for controlled drug delivery system

Title
Electrospun poly (lactic-co-glycolic acid)(PLGA) microparticles for controlled drug delivery system
Authors
Lee J.Y.Lee M.H.Park W.H.Min B.M.Lee S.J.
Ewha Authors
이승진
SCOPUS Author ID
이승진scopus
Issue Date
2004
Journal Title
Transactions - 7th World Biomaterials Congress
Indexed
SCOPUS scopus
Abstract
The use of electrospinning technique for the fabrication of poly(lactic-co-glycolic acid) (PLGA) microparticles for drug delivery system and coating materials in order to reduce initial burst release was discussed. It was observed that the morphology of PLGA microparticles was influenced by parameters such as polymer concentration, electrospinning voltage and air gap distance. It was found that the initial burst of PLLA particles could be reduced by coating with PLGA microparticles. The results show that electrospinning of PLGA microparticles could be used as controlled drug delivery system for sustained release and release controlling modality.
ISBN
1877040193; 9781877040191
Appears in Collections:
약학대학 > 약학과 > Journal papers
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