View : 39 Download: 6

Classification of ginseng berry (Panax ginseng C.A. MEYER) extract using 1H NMR spectroscopy and its inhibition of lipid accumulation in 3 T3-L1 cells

Title
Classification of ginseng berry (Panax ginseng C.A. MEYER) extract using 1H NMR spectroscopy and its inhibition of lipid accumulation in 3 T3-L1 cells
Authors
Yang S.O.Park H.R.Sohn E.S.Lee S.W.Kim H.D.Kim Y.C.Kim K.H.Na S.W.Choi H.-K.Arasu M.V.Kim Y.O.
Ewha Authors
양승옥
SCOPUS Author ID
양승옥scopus
Issue Date
2015
Journal Title
BMC Complementary and Alternative Medicine
ISSN
1472-6882JCR Link
Citation
pp. 1 - 6
Keywords
MaturationMetabolite profilingObesityPanax ginseng berry
Publisher
BioMed Central Ltd.
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Background: Panax ginseng is a famous traditional medicine in Korea for its beneficial effect on obesity, cardiac and liver associated diseases. The aim of this study was to investigate the metabolite in Panax ginseng (P. ginseng, Aralicaceae) berries depending on the ripen stages and evaluate its potential inhibition on adipocyte differentiation in 3 T3-L1 cells. Methods: Different ripening stage samples of P. ginseng berry were analyzed through global metabolite profiling by NMR spectroscopy. Lipid accumulation in the cells was analyzed by Oil Red O staining. Results: The PLS-DA clearly distinguished P. ginseng berry extract (PGBE) according to the partial ripe (PR), ripe(R) and fully ripe (FR) stage. Lipid accumulation of PGBE was examined by measuring triglyceride content and Oil-Red O staining. These results suggested that the FR stage of PGBE decrease in lipid accumulation during adipocyte differentiation and the amount of threonine, asparagine, fumarate, tyraine, tyrosine, and phenylalanine increased with longer ripening of ginseng berries. Conclusion: Metabolite profiling of P. ginseng was identified by 1H NMR spectra. P. ginseng extract efficiently inhibits adipogenesis in 3 T3-L1 adipocytes concluded that the P. ginseng has the antiobesity properties. © 2014 Yang et al.; licensee BioMed Central Ltd.
DOI
10.1186/1472-6882-14-455
Appears in Collections:
엘텍공과대학 > 식품공학전공 > Journal papers
Files in This Item:
001.pdf(1.34 MB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE