View : 36 Download: 0

Seizure localization using three-dimensional surface projections of intracranial EEG power

Title
Seizure localization using three-dimensional surface projections of intracranial EEG power
Authors
Lee H.W.Youngblood M.W.Farooque P.Han X.Jhun S.Chen W.C.Goncharova I.Vives K.Spencer D.D.Zaveri H.Hirsch L.J.Blumenfeld H.
Ewha Authors
이향운
SCOPUS Author ID
이향운scopus
Issue Date
2013
Journal Title
NeuroImage
ISSN
1053-8119JCR Link
Citation
vol. 83, pp. 616 - 626
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Intracranial EEG (icEEG) provides a critical road map for epilepsy surgery but it has become increasingly difficult to interpret as technology has allowed the number of icEEG channels to grow. Borrowing methods from neuroimaging, we aimed to simplify data analysis and increase consistency between reviewers by using 3D surface projections of intracranial EEG poweR (3D-SPIER). We analyzed 139 seizures from 48 intractable epilepsy patients (28 temporal and 20 extratemporal) who had icEEG recordings, epilepsy surgery, and at least one year of post-surgical follow-up. We coregistered and plotted icEEG β frequency band signal power over time onto MRI-based surface renderings for each patient, to create color 3D-SPIER movies. Two independent reviewers interpreted the icEEG data using visual analysis vs. 3D-SPIER, blinded to any clinical information. Overall agreement rates between 3D-SPIER and icEEG visual analysis or surgery were about 90% for side of seizure onset, 80% for lobe, and just under 80% for sublobar localization. These agreement rates were improved when flexible thresholds or frequency ranges were allowed for 3D-SPIER, especially for sublobar localization. Interestingly, agreement was better for patients with good surgical outcome than for patients with poor outcome. Localization using 3D-SPIER was measurably faster and considered qualitatively easier to interpret than visual analysis. These findings suggest that 3D-SPIER could be an improved diagnostic method for presurgical seizure localization in patients with intractable epilepsy and may also be useful for mapping normal brain function. © 2013 Elsevier Inc.
DOI
10.1016/j.neuroimage.2013.07.010
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE