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Dual-energy CT in the assessment of mediastinal lymph nodes: Comparative study of virtual non-contrast and true non-contrast images

Title
Dual-energy CT in the assessment of mediastinal lymph nodes: Comparative study of virtual non-contrast and true non-contrast images
Authors
Yoo S.Y.Kim Y.Cho H.H.Choi M.J.Shim S.S.Lee J.K.Baek S.Y.
Ewha Authors
백승연김유경이정경심성신조현혜
SCOPUS Author ID
백승연scopus; 김유경scopus; 이정경scopus; 심성신scopus
Issue Date
2013
Journal Title
Korean Journal of Radiology
ISSN
1229-6929JCR Link
Citation
vol. 14, no. 3, pp. 532 - 539
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
Objective: To evaluate the reliability of virtual non-contrast (VNC) images reconstructed from contrast-enhanced, dual-energy scans compared with true non-contrast (TNC) images in the assessment of high CT attenuation or calcification of mediastinal lymph nodes. Materials and Methods: A total of 112 mediastinal nodes from 45 patients who underwent non-contrast and dual-energy contrast-enhanced scans were analyzed. Node attenuation in TNC and VNC images was compared both objectively, using computed tomography (CT) attenuation, and subjectively, via visual scoring (0, attenuation ≤ the aorta; 1, > the aorta; 2, calcification). The relationship among attenuation difference between TNC and VNC images, CT attenuation in TNC images, and net contrast enhancement (NCE) was analyzed. Results: CT attenuation in TNC and VNC images showed moderate agreement (intraclass correlation coefficient, 0. 612). The mean absolute difference was 7. 8 ± 7. 6 Hounsfield unit (HU) (range, 0-36 HU), and the absolute difference was equal to or less than 10 HU in 65. 2% of cases (73/112). Visual scores in TNC and VNC images showed fair agreement (k value, 0. 335). Five of 16 nodes (31. 3%) which showed score 1 (n = 15) or 2 (n = 1) in TNC images demonstrated score 1 in VNC images. The TNC-VNC attenuation difference showed a moderate positive correlation with CT attenuation in TNC images (partial correlation coefficient [PCC] adjusted by NCE: 0. 455) and a weak negative correlation with NCE (PCC adjusted by CT attenuation in TNC: -0. 245). Conclusion: VNC images may be useful in the evaluation of mediastinal lymph nodes by providing additional information of high CT attenuation of nodes, although it is underestimated compared with TNC images.
DOI
10.3348/kjr.2013.14.3.532
Appears in Collections:
의과대학 > 의학과 > Journal papers
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