Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박상희 | * |
dc.date.accessioned | 2016-08-28T10:08:51Z | - |
dc.date.available | 2016-08-28T10:08:51Z | - |
dc.date.issued | 2013 | * |
dc.identifier.issn | 0513-5796 | * |
dc.identifier.other | OAK-10016 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223663 | - |
dc.description.abstract | A 31-year-old Korean male presented with altered consciousness and severe headache. Brain MRI delineated focal leptomeningeal enhancement without any intrace-rebral lesions. Diagnosis was made based on a brain biopsy showing anaplastic large cell lymphoma (ALCL), immunohistochemical stains revealing positivity for anaplastic lymphoma kinase (ALK) and an absence of involvement in any other organs; specifically, the primary central nervous system ALKALCL. Complete remission was achieved following 5 cycles of systemic chemotherapy with a high dose of Methotrexate and a simultaneous 7 cycles of intrathecal triple chemotherapy. Diagnosis of primary leptomeningeal ALK+ALCL is challenging given its rarity and non-specific symptoms along with non-pathognomonic radiologic findings. We present the first case of primary leptomeningeal ALK-positive ALCL where the clinical course, pathologic characteristics and treatment modality are described as well as a review of literature. © Yonsei University College of Medicine 2013. | * |
dc.language | English | * |
dc.title | Primary central nervous system ALK positive anaplastic large cell lymphoma with predominantly leptomeningeal involvement in an adult | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 54 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 791 | * |
dc.relation.lastpage | 796 | * |
dc.relation.journaltitle | Yonsei Medical Journal | * |
dc.identifier.doi | 10.3349/ymj.2013.54.3.791 | * |
dc.identifier.wosid | WOS:000317942600038 | * |
dc.identifier.scopusid | 2-s2.0-84875890781 | * |
dc.author.google | Park J.S. | * |
dc.author.google | Park H. | * |
dc.author.google | Park S. | * |
dc.author.google | Kim S.J. | * |
dc.author.google | Seol H.J. | * |
dc.author.google | Ko Y.-H. | * |
dc.contributor.scopusid | 박상희(12041890800) | * |
dc.date.modifydate | 20240220112152 | * |