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dc.contributor.author박상희-
dc.date.accessioned2016-08-28T10:08:51Z-
dc.date.available2016-08-28T10:08:51Z-
dc.date.issued2013-
dc.identifier.issn0513-5796-
dc.identifier.otherOAK-10016-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/223663-
dc.description.abstractA 31-year-old Korean male presented with altered consciousness and severe headache. Brain MRI delineated focal leptomeningeal enhancement without any intrace-rebral lesions. Diagnosis was made based on a brain biopsy showing anaplastic large cell lymphoma (ALCL), immunohistochemical stains revealing positivity for anaplastic lymphoma kinase (ALK) and an absence of involvement in any other organs; specifically, the primary central nervous system ALKALCL. Complete remission was achieved following 5 cycles of systemic chemotherapy with a high dose of Methotrexate and a simultaneous 7 cycles of intrathecal triple chemotherapy. Diagnosis of primary leptomeningeal ALK+ALCL is challenging given its rarity and non-specific symptoms along with non-pathognomonic radiologic findings. We present the first case of primary leptomeningeal ALK-positive ALCL where the clinical course, pathologic characteristics and treatment modality are described as well as a review of literature. © Yonsei University College of Medicine 2013.-
dc.languageEnglish-
dc.titlePrimary central nervous system ALK positive anaplastic large cell lymphoma with predominantly leptomeningeal involvement in an adult-
dc.typeArticle-
dc.relation.issue3-
dc.relation.volume54-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage791-
dc.relation.lastpage796-
dc.relation.journaltitleYonsei Medical Journal-
dc.identifier.doi10.3349/ymj.2013.54.3.791-
dc.identifier.wosidWOS:000317942600038-
dc.identifier.scopusid2-s2.0-84875890781-
dc.author.googlePark J.S.-
dc.author.googlePark H.-
dc.author.googlePark S.-
dc.author.googleKim S.J.-
dc.author.googleSeol H.J.-
dc.author.googleKo Y.-H.-
dc.contributor.scopusid박상희(12041890800)-
dc.date.modifydate20180329113451-
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의과대학 > 의학과 > Journal papers
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