Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이동현 | - |
dc.date.accessioned | 2016-08-28T10:08:50Z | - |
dc.date.available | 2016-08-28T10:08:50Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0042-1138 | - |
dc.identifier.other | OAK-10007 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223654 | - |
dc.description.abstract | Introduction: The aim of this study was to identify patients with low-volume Gleason score 3+4 (GS3+4) prostate cancer (PCa) who may be candidates for active surveillance (AS) by analyzing the incidence of upgrading and upstaging following radical prostatectomy (RP). Patients and Methods: Of 907 patients who underwent RP at our institute over the last 5 years, 66 men diagnosed with low-volume GS3+4 PCa at needle biopsy were identified. The incidence of upstaging and upgrading was assessed. Results: The overall rate of upgrading and upstaging was 31.8 and 25.6%, respectively. Preoperative PSA levels were significantly higher in patients who were upgraded (p = 0.015). The optimal preoperative PSA cutoff level for the prediction of upgrading was 4.73 ng/ml (sensitivity 85.7%, specificity 57.8%). Patients with <15% of maximum cores positive had significantly lower upstaging rate than those with >15% of maximum cores positive (p = 0.035). Clinical stage and number of positive cores had marginal association with upgrading and upstaging statistically (p = 0.061 and 0.081, respectively). Conclusions: In patients with low-volume GS3+4 PCa at biopsy, underestimation may be effectively avoided when we select patients with PSA <4.73 and % maximum cancer involvement on positive cores <15%. Copyright © 2013 S. Karger AG, Basel. | - |
dc.language | English | - |
dc.title | Incidence of upgrading and upstaging in patients with low-volume Gleason score 3+4 prostate cancers at biopsy: Finding a new group eligible for active surveillance | - |
dc.type | Article | - |
dc.relation.issue | 3 | - |
dc.relation.volume | 90 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 301 | - |
dc.relation.lastpage | 305 | - |
dc.relation.journaltitle | Urologia Internationalis | - |
dc.identifier.doi | 10.1159/000345292 | - |
dc.identifier.wosid | WOS:000317906000010 | - |
dc.identifier.scopusid | 2-s2.0-84876852020 | - |
dc.author.google | Park H.J. | - |
dc.author.google | Ha Y.-S. | - |
dc.author.google | Park S.Y. | - |
dc.author.google | Kim Y.T. | - |
dc.author.google | Lee T.Y. | - |
dc.author.google | Kim J.H. | - |
dc.author.google | Lee D.-H. | - |
dc.author.google | Kim W.-J. | - |
dc.author.google | Kim I.Y. | - |
dc.contributor.scopusid | 이동현(24341048900;57202299352) | - |
dc.date.modifydate | 20230331134421 | - |