Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박혜영 | - |
dc.date.accessioned | 2016-08-28T10:08:38Z | - |
dc.date.available | 2016-08-28T10:08:38Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.other | OAK-9884 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223543 | - |
dc.description.abstract | A novel series of aryl sulfonylpiperazine derivatives (5-15) were synthesized as 5-HT6 ligands. In vitro assay was evaluated by measuring the 5-HT-induced Ca2+ increases using HeLa cell line expressing the cloned human 5-HT6 receptor, and the compound 13 showed potent 5-HT6 receptor antagonistic effect with IC50 value of 3.9 μM. Compound 13 also showed good selectivity on the 5-HT6 over 5-HT4 and 5-HT7 receptors. | - |
dc.language | English | - |
dc.title | Synthesis and inhibition effects on 5-HT6 receptor of benzothiazole derivatives | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 34 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 495 | - |
dc.relation.lastpage | 499 | - |
dc.relation.journaltitle | Bulletin of the Korean Chemical Society | - |
dc.identifier.doi | 10.5012/bkcs.2013.34.2.495 | - |
dc.identifier.wosid | WOS:000316430200031 | - |
dc.identifier.scopusid | 2-s2.0-84874525087 | - |
dc.author.google | Hayat F. | - |
dc.author.google | Yoo E. | - |
dc.author.google | Rhim H. | - |
dc.author.google | Choo H.-Y.P. | - |
dc.contributor.scopusid | 박혜영(34972649500;57200273796) | - |
dc.date.modifydate | 20230411110509 | - |