View : 94 Download: 0

Clinical outcomes and risk factors of post-polypectomy coagulation syndrome: A multicenter, retrospective, case-control study

Title
Clinical outcomes and risk factors of post-polypectomy coagulation syndrome: A multicenter, retrospective, case-control study
Authors
Cha J.M.Lim K.S.Lee S.H.Joo Y.E.Hong S.P.Kim T.I.Kim H.G.Park D.I.Kim S.E.Yang D.H.Shin J.E.
Ewha Authors
김성은
SCOPUS Author ID
김성은scopus
Issue Date
2013
Journal Title
Endoscopy
ISSN
0013-726XJCR Link
Citation
vol. 45, no. 3, pp. 202 - 207
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Background and study aims: Post-polypectomy coagulation syndrome (PPCS) is a well known complication of colonoscopic polypectomy. However, no previous studies have reported on the clinical outcomes or risk factors of PPCS. The aim of the current study was to analyze the clinical outcomes and risk factors of PPCS developing after a colonoscopic polypectomy. Patients and methods: Data for all patients who underwent colonoscopic polypectomies and required hospitalization in nine university hospitals were analyzed retrospectively. The incidence, clinicopathological characteristics, and clinical outcomes of PPCS cases were examined. Additionally, patients who developed PPCS were compared with controls who were matched by age and sex, in order to assess for possible risk factors. Results: The rate of PPCS that required hospitalization after colonoscopic polypectomy was 0.7/1000. All patients with PPCS were treated medically without the need for surgical interventions. The median durations of therapeutic fasting, hospitalization, and antibiotic use were 3 days, 5.5 days, and 7 days, respectively. The rates of major PPCS and mortality were 2.9 % and 0 %, respectively. On multivariate analysis, hypertension (OR = 3.023, 95 %CI 1.034 - 8.832), large lesion size (OR = 2.855, 95 %CI 1.027 - 7.937), and non-polypoid configuration (OR = 3.332, 95 %CI 1.029 - 10.791) were found to be independent risk factors related to the development of PPCS. Conclusions: In this study, the rates of major PPCS and mortality were only 2.9 % and 0 %, respectively. Hypertension, large lesion size, and non-polypoid configuration of the lesion were independently associated with PPCS. Therefore, patients may be reassured by the excellent prognosis of PPCS, while endoscopists should be especially careful when performing colonoscopic polypectomies in patients with hypertension or large and non-polypoid lesions. © Georg Thieme Verlag KG Stuttgart · New York.
DOI
10.1055/s-0032-1326104
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE