View : 35 Download: 0

Pathologic implications of prostatic anterior fat pad

Title
Pathologic implications of prostatic anterior fat pad
Authors
Jeong J.Choi E.Y.Kang D.I.Ercolani M.Lee D.H.Kim W.-J.Kim I.Y.
Ewha Authors
이동현
SCOPUS Author ID
이동현scopus
Issue Date
2013
Journal Title
Urologic Oncology: Seminars and Original Investigations
ISSN
1078-1439JCR Link
Citation
vol. 31, no. 1, pp. 63 - 67
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Objective: Lymph node status has significant pathologic implications in patients with prostate cancer. In this study, we have performed pathologic analysis of prostatic anterior fat pad (PAFP) excised during robot-assisted radical prostatectomy (RARP) to investigate the potential role of AFP on pathologic staging of prostate cancer. Methods: A total of 258 consecutive patients underwent PAFP excision during RARP between July 2007 and June 2009. PAFP was removed and submitted en bloc to the pathology department and evaluated for the presence of lymphoid tissue and metastatic prostate cancer. Retrospective chart review was performed for all patients. Results: Of the 258 patients, 30 (11.6%) had 1 or 2 PAFP lymph nodes and 228 (88.4%) men showed no lymphoid tissue in their PAFPs. Preoperatively, mean PSA level was higher in the former group. There were no significant pathologic differences between the 2 groups. Among the 30 patients with PAFP lymph nodes, 3 were positive for metastatic prostate cancer. All 3 of these patients had high-risk features preoperatively. In 1 patient, the pelvic lymph nodes were negative for metastatic prostate cancer. At 2-year follow up, PSA level of this patient was undetectable. Conclusions: Herein, we demonstrated that the PAFP contained lymph nodes in over 11% of the patients undergoing RARP at our institution. Prostate cancer was upstaged in 1 patient as a result of PAFP excision. Since this patient is free of biochemical recurrence at 2 years, routine excision and pathologic analysis of PAFP should be considered in prostate cancer patients undergoing radical prostatectomy. © 2013 Elsevier Inc.
DOI
10.1016/j.urolonc.2010.09.003
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE