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Relationship between maternal sodium intake and blood lead concentration during pregnancy

Title
Relationship between maternal sodium intake and blood lead concentration during pregnancy
Authors
Lee Y.A.Hwang J.-Y.Kim H.Kim K.N.Ha E.-H.Park H.Ha M.Kim Y.Hong Y.-C.Chang N.
Ewha Authors
하은희장남수박혜숙김혜숙
SCOPUS Author ID
하은희scopus; 장남수scopus; 박혜숙scopus; 김혜숙scopus
Issue Date
2013
Journal Title
British Journal of Nutrition
ISSN
0007-1145JCR Link
Citation
vol. 109, no. 5, pp. 853 - 858
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Pb is released from bone stores during pregnancy, which constitutes a period of increased bone resorption. A high Na intake has been found to be negatively associated with Ca and adversely associated with bone metabolism. It is possible that a high Na intake during pregnancy increases the blood Pb concentration; however, no previous study has reported on the relationship between Na intake and blood Pb concentration. We thus have investigated this relationship between Na intake and blood Pb concentrations, and examined whether this relationship differs with Ca intake in pregnant Korean women. Blood Pb concentrations were analysed in 1090 pregnant women at mid-pregnancy. Dietary intakes during mid-pregnancy were estimated by a 24 h recall method covering the use of dietary supplements. Blood Pb concentrations in whole-blood samples were analysed using graphite furnace atomic absorption spectrophotometry. Multiple regression analysis performed after adjustment for covariates revealed that maternal Na intake was positively associated with blood Pb concentration during pregnancy, but only when Ca intake was below the estimated average requirement for pregnant Korean women (P= 0.001). The findings of the present study suggest that blood Pb concentration during pregnancy could be minimised by dietary recommendations that include decreased Na and increased Ca intakes. Copyright © The Authors 2012.
DOI
10.1017/S0007114512002760
Appears in Collections:
의과대학 > 의학과 > Journal papers
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