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Incidence and short-term mortality from perforated peptic ulcer in Korea: A population-based study

Title
Incidence and short-term mortality from perforated peptic ulcer in Korea: A population-based study
Authors
Bae S.J.Shim K.-N.Kim N.Kang J.M.Kim D.-S.Kim K.-M.Cho Y.K.Jung S.W.
Ewha Authors
심기남배승진
SCOPUS Author ID
심기남scopus; 배승진scopus
Issue Date
2012
Journal Title
Journal of Epidemiology
ISSN
0917-5040JCR Link
Citation
vol. 22, no. 6, pp. 508 - 516
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Background: Perforated peptic ulcer (PPU) is associated with serious health and economic outcomes. However,few studies have estimated the incidence and health outcomes of PPU using a nationally representative sample in Asia. We estimated age- and sex-specific incidence and short-term mortality from PPU among Koreans and investigated the risk factors for mortality associated with PPU development. Methods: A retrospective population-based study was conducted from 2006 through 2007 using the Korean National Health Insurance claims database. A diagnostic algorithm was derived and validated to identify PPU patients, and PPU incidence rates and 30-daymortality rates were determined. Results: From 2006 through 2007, the PPU incidence rate per 100 000 population was 4.4; incidence among men (7.53) was approximately 6 times that among women (1.24). Incidence significantly increased with advanced age,especially among women older than 50 years. Among 4258 PPU patients, 135 (3.15%)died within 30 days of the PPU event. The 30-day mortality rate increased with advanced age and reached almost 20% for patients older than 80 years. The 30-day mortality rate was 10% for women and 2% for men. Older age, being female, and higher comorbidity were independently associated with 30-day mortality rate among PPU patients in Korea. Conclusions: Special attention should be paid to elderly women with high comorbidity who develop PPU. © 2012 by the Japan Epidemiological Association.
DOI
10.2188/jea.JE20120056
Appears in Collections:
의과대학 > 의학과 > Journal papers
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