Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상기 | * |
dc.contributor.author | 김주현 | * |
dc.date.accessioned | 2016-08-28T10:08:19Z | - |
dc.date.available | 2016-08-28T10:08:19Z | - |
dc.date.issued | 2012 | * |
dc.identifier.issn | 0039-7881 | * |
dc.identifier.other | OAK-8914 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/222760 | - |
dc.description.abstract | Tandem transformations of nitriles into various N-heterocycles have been accomplished through the reaction of electrophiles with Blaise reaction intermediates formed in situ. The reaction of the Blaise reaction intermediates with propiolates gives 2-pyridones through consecutive C- and N-nucleophilic reactions. The tandem reactions of the Blaise reaction intermediate with 1,3-enynes proceed through C-nucleophilic addition followed by an electrocyclization-aromatization cascade to give pyridines. Exocyclic enamino esters can be prepared by transformations of ω-chloroalkyl nitriles through chemoselective intramolecular alkylation of the Blaise reaction intermediate. Palladium-catalyzed intramolecular arylations or copper-catalyzed intermolecular cross-coupling reactions of the Blaise reaction intermediate give a range of indole derivatives. Combinations of tandem alkylations and palladium-catalyzed couplings of the Blaise reaction intermediates of ω-chloroalkyl nitriles give N-fused indoles. © Georg Thieme Verlag Stuttgart · New York. | * |
dc.language | English | * |
dc.title | Tandem transformations of nitriles into N-heterocyclic compounds by electrophilic trapping of Blaise reaction intermediates | * |
dc.type | Article | * |
dc.relation.issue | 12 | * |
dc.relation.volume | 44 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1809 | * |
dc.relation.lastpage | 1817 | * |
dc.relation.journaltitle | Synthesis (Germany) | * |
dc.identifier.doi | 10.1055/s-0031-1290814 | * |
dc.identifier.wosid | WOS:000305391500005 | * |
dc.identifier.scopusid | 2-s2.0-84861847435 | * |
dc.author.google | Kim J. | * |
dc.author.google | Chun Y. | * |
dc.author.google | Shin H. | * |
dc.author.google | Lee S.-G. | * |
dc.contributor.scopusid | 이상기(15082786300) | * |
dc.contributor.scopusid | 김주현(57207894284) | * |
dc.date.modifydate | 20240123104103 | * |