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Ovarian cryopreservation

Title
Ovarian cryopreservation
Authors
Jeong K.Aslan E.Ozkaya E.Sonmezer M.Oktay K.
Ewha Authors
정경아
SCOPUS Author ID
정경아scopus
Issue Date
2012
Journal Title
Minerva Medica
ISSN
0026-4806JCR Link
Citation
vol. 103, no. 1, pp. 37 - 46
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Cryopreservation of ovarian tissue and future autotransplantation are new promising strategies for fertility preservation in various malignant and non-malignant diseases facing the risk of ovarian failure. Ovarian cortrical tissue pieces or intact whole ovary can be removed by laparoscopy without any significant delay in chemotherapy. Slow freezing and vitrification methods are developed to avoid damage to follicles. Ovarian tissue can be transplanted in an orthotopic or heterotopic location when the patient is cured from the disease. Autotransplantation can be performed if absence of malignant cells in the graft is confirmed. Although the procedures are still experimental, ovarian cryopreservation is the single option in prepubertal girls who have not sexual maturity. Earlier team approach of oncologists and reproductive endocrinologists may provide a more successful and professional way of fertility preservation.
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의학전문대학원 > 의학과 > Journal papers
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