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Ectopic paragonimiasis from 400-year-old female mummy of Korea
- Ectopic paragonimiasis from 400-year-old female mummy of Korea
- Shin D.H.; Oh C.S.; Lee S.J.; Lee E.-J.; Yim S.G.; Kim M.J.; Kim Y.-S.; Lee S.D.; Lee Y.S.; Lee H.J.; Seo M.
- Ewha Authors
- SCOPUS Author ID
- Issue Date
- Journal Title
- Journal of Archaeological Science
- vol. 39, no. 4, pp. 1103 - 1110
- SCIE; SSCI; AHCI; SCOPUS
- Of the parasite eggs discovered in ancient samples from Korean archaeological sites, Paragonimus spp. are of particular importance in that they are regarded as one of the most insidious trematode infection sources. Although their infection prevalence decreased rapidly in the early 20th century, archaeoparasitological studies on the species are still required, as historical knowledge of paragonimiasis remains far from comprehensive. Fortunately, we recently were given a chance to examine a medieval Korean mummy in a good state of preservation. Using morphological techniques, we discovered evidence of ectopic paragonimiasis in the sample from the 17th-century female. When the ITS 2 gene was extracted, amplified and sequenced from Paragonimus eggs, it showed 100% homology to the sequences of modern Paragonimus westermani reported from Korea and Japan, forming a cluster distinct from South Asian P.westermani. Our report is the first-ever analysis of ancient Paragonimus DNA from any archaeological field in the world. The ectopic paragonimiasis diagnosis made in this study, especially involving the liver sample, also is the first of its kind in archaeoparasitology. © 2011 Elsevier Ltd.
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