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FX: An RNA-seq analysis tool on the cloud

Title
FX: An RNA-seq analysis tool on the cloud
Authors
Hong D.Rhie A.Park S.Lee J.Ju Y.S.Kim S.Yu S.Bleazard T.Park H.Rhee H.Chong H.Yang K.Lee Y.Kim I.Lee J.S.Kim J.Seo J.
Ewha Authors
박현석
SCOPUS Author ID
박현석scopus
Issue Date
2012
Journal Title
Bioinformatics
ISSN
1367-4803JCR Link
Citation
vol. 28, no. 5, pp. 721 - 723
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Summary: FX is an RNA-Seq analysis tool, which runs in parallel on cloud computing infrastructure, for the estimation of gene expression levels and genomic variant calling. In the mapping of short RNA-Seq reads, FX uses a transcriptome-based reference primarily, generated from ~160 000 mRNA sequences from RefSeq, UCSC and Ensembl databases. This approach reduces the misalignment of reads originating from splicing junctions. Unmapped reads not aligned on known transcripts are then mapped on the human genome reference. FX allows analysis of RNA-Seq data on cloud computing infrastructures, supporting access through a user-friendly web interface. © The Author 2012. Published by Oxford University Press. All rights reserved.
DOI
10.1093/bioinformatics/bts023
Appears in Collections:
엘텍공과대학 > 컴퓨터공학과 > Journal papers
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