Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이윤실 | * |
dc.date.accessioned | 2016-08-28T12:08:01Z | - |
dc.date.available | 2016-08-28T12:08:01Z | - |
dc.date.issued | 2012 | * |
dc.identifier.issn | 0197-8462 | * |
dc.identifier.other | OAK-8524 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/222417 | - |
dc.description.abstract | Epidemiological studies have suggested that extremely low-frequency magnetic fields (ELF-MF) are associated with an increased incidence of cancer. Studies using in vitro systems have reported mixed results for the effects of ELF-MF alone, and the World Health Organization (WHO) Research Agenda published in 2007 suggested that high priority research should include an evaluation of the co-carcinogenic effects of ELF-MF exposure using in vitro models. Here, the carcinogenic potential of ELF-MF exposure alone and in combination with various stress factors was investigated in NIH3T3 mouse fibroblasts using an in vitro cellular transformation assay. NIH3T3 cells were exposed to a 60Hz ELF-MF (1mT) alone or in combination with ionizing radiation (IR), hydrogen peroxide (H 2O 2), or c-Myc overexpression, and the resulting number of anchorage-independent colonies was counted. A 4h exposure of NIH3T3 cells to ELF-MF alone produced no cell transformation. Moreover, ELF exposure did not influence the transformation activity of IR, H 2O 2, or activated c-Myc in our in vitro assay system, suggesting that 1mT ELF-MF did not affect any additive or synergistic transformation activities in combination with stress factors such as IR, H 2O 2, or activated c-Myc in NIH3T3 cells. © 2011 Wiley Periodicals, Inc. | * |
dc.language | English | * |
dc.title | Combined effects of 60Hz electromagnetic field exposure with various stress factors on cellular transformation in NIH3T3 cells | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 33 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 207 | * |
dc.relation.lastpage | 214 | * |
dc.relation.journaltitle | Bioelectromagnetics | * |
dc.identifier.doi | 10.1002/bem.20700 | * |
dc.identifier.wosid | WOS:000300972100002 | * |
dc.identifier.scopusid | 2-s2.0-84857797503 | * |
dc.author.google | Lee H.-J. | * |
dc.author.google | Jin Y.B. | * |
dc.author.google | Lee J.S. | * |
dc.author.google | Choi J.-I. | * |
dc.author.google | Lee J.-W. | * |
dc.author.google | Myung S.H. | * |
dc.author.google | Lee Y.-S. | * |
dc.contributor.scopusid | 이윤실(17137192000) | * |
dc.date.modifydate | 20240130115944 | * |