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Choroidal thickness in both eyes of patients with unilaterally active central serous chorioretinopathy

Title
Choroidal thickness in both eyes of patients with unilaterally active central serous chorioretinopathy
Authors
Kim Y.T.Kang S.W.Bai K.H.
Ewha Authors
김윤택
SCOPUS Author ID
김윤택scopus
Issue Date
2011
Journal Title
Eye
ISSN
0950-222XJCR Link
Citation
vol. 25, no. 12, pp. 1635 - 1640
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Objective To assess the change in the choroidal thickness of the unaffected eyes in patients with unilateral central serous chorioretinopathy (CSC). Methods Thirty eyes with unilateral idiopathic CSC and 30 age-matched normal eyes were included in this study. Choroidal thickness was evaluated from images obtained by enhanced depth image optical coherence tomography. The choroidal thicknesses of the affected eyes, unaffected eyes, and normal eyes were analyzed. Choroidal vascular dilation and hyperpermeability on indocyanine green angiography (ICGA) were analyzed and correlated with the changes in choroidal thickness. Results The mean choroidal thicknesses of the affected eyes, unaffected fellow eyes, and normal individuals were 445.58±100.25, 378.35±117.44, and 266.80±55.45 lm, respectively. Compared with normal eyes, subfoveal choroidal thickness was increased significantly in the eyes with active CSC and in the unaffected fellow eyes (P<0.001 in both groups). The choroidal thickness was significantly greater in the eyes with active CSC than in the unaffected fellow eyes (P=0.003). ICGA revealed choroidal vascular hyperpermeability in 28 (93.3%) eyes with CSC and in 23 (73.3%) unaffected fellow eyes. Choroidal vascular dilation was detected in 21 (70.0%) eyes with CSC and in 18 (60.0%) unaffected fellow eyes. Conclusion Increased choroidal thickness in patients with unilateral CSC was noted not only in the affected eyes, but also in the unaffected fellow eyes. The results of this study suggest that CSC might be an essentially bilateral disorder. © 2011 Macmillan Publishers Limited. All rights reserved.
DOI
10.1038/eye.2011.258
Appears in Collections:
의과대학 > 의학과 > Journal papers
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