Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 심효섭 | - |
dc.date.accessioned | 2016-08-28T12:08:27Z | - |
dc.date.available | 2016-08-28T12:08:27Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0169-5002 | - |
dc.identifier.other | OAK-8112 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/222067 | - |
dc.description.abstract | Background: The purpose of this study was to clarify the relationship between the tumor infiltrating lymphocytes and clinical outcome in patients with thymic carcinoma. Methods: Tissue specimens from 32 patients who underwent surgical resection for thymic carcinoma were immunohistochemically analyzed for CD4, CD8 and CD20 expression. Results: Tumor-infiltrating lymphocytes were generally more abundant in the stroma. The patients with low CD4+ lymphocytes (p= 0.037) and low CD20+ lymphocytes (p= 0.045) within tumor stroma showed poor survival. Furthermore, concurrent low levels of CD4+ and CD20+ (p= 0.014), CD8+ and CD20+ (p= 0.025), and, CD4+, CD8+, and CD20+ (p= 0.025) in tumor stroma were significantly associated with poor prognosis when compared to the others group. Conclusion: Our results indicate that infiltrating CD4+, CD8+, and CD20+ lymphocytes in cancer stroma may cooperate to suppress cancer progression and their presence together appear to be prognostic factor in thymic carcinoma. © 2011 Elsevier Ireland Ltd. | - |
dc.language | English | - |
dc.title | Prognostic effect of stromal lymphocyte infiltration in thrymic carcinoma | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 74 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 338 | - |
dc.relation.lastpage | 343 | - |
dc.relation.journaltitle | Lung Cancer | - |
dc.identifier.doi | 10.1016/j.lungcan.2011.03.008 | - |
dc.identifier.wosid | WOS:000296684300030 | - |
dc.identifier.scopusid | 2-s2.0-80053633053 | - |
dc.author.google | Shim H.S. | - |
dc.author.google | Byun C.S. | - |
dc.author.google | Bae M.K. | - |
dc.author.google | Lee C.Y. | - |
dc.author.google | Park I.K. | - |
dc.author.google | Kim D.J. | - |
dc.author.google | Chung K.Y. | - |
dc.author.google | Lee J.G. | - |
dc.contributor.scopusid | 심효섭(8701798400 ) | - |
dc.date.modifydate | 20211210153140 | - |