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Is Intra-Articular Multimodal Drug Injection Effective in Pain Management After Total Knee Arthroplasty?. A Randomized, Double-Blinded, Prospective Study

Title
Is Intra-Articular Multimodal Drug Injection Effective in Pain Management After Total Knee Arthroplasty?. A Randomized, Double-Blinded, Prospective Study
Authors
Joo J.-H.Park J.-W.Kim J.-S.Kim Y.-H.
Ewha Authors
김영후김준식박장원
SCOPUS Author ID
김영후scopus; 김준식scopus; 박장원scopus
Issue Date
2011
Journal Title
Journal of Arthroplasty
ISSN
0883-5403JCR Link
Citation
vol. 26, no. 7, pp. 1095 - 1099
Indexed
SCIE; SCOPUS WOS scopus
Abstract
We performed a prospective, double-blinded, randomized, and controlled study to assess the clinical efficacy and safety of intra-articular multimodal drug injection after total knee arthroplasty. Two hundred eighty-six patients undergoing simultaneous bilateral total knee arthroplasty were randomized to receive the injection of multimodal drugs in one knee and normal saline solution as a placebo in the contralateral knee. All patients received patient-controlled analgesia for 48 hours after surgery, followed by standard analgesia. Visual analog scores for pain during activity and rest and for patient satisfaction were recorded. The range of motion and blood loss were also recorded. Intraoperative intra-articular injection of multimodal drugs into the knee did not improve patient pain and satisfaction, range of motion, or blood loss compared with the placebo control. © 2011 Elsevier Inc.
DOI
10.1016/j.arth.2011.03.052
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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