Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이진화 | * |
dc.date.accessioned | 2016-08-28T12:08:05Z | - |
dc.date.available | 2016-08-28T12:08:05Z | - |
dc.date.issued | 2011 | * |
dc.identifier.issn | 1027-3719 | * |
dc.identifier.other | OAK-7854 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221856 | - |
dc.description.abstract | SETTING: Eleven referring hospitals in South Korea. OBJECTIVE: To compare therapeutic responses in chronic obstructive pulmonary disease (COPD) subgroups, classifi ed by diffusing capacity of the lung for carbon monoxide (DL CO) and lung volume. DESIGN: A total of 130 stable male COPD patients were classified into four subgroups according to baseline DLCO and residual volume/total lung capacity (RV/TLC) ratio. We compared therapeutic responses to short acting β2-agonist (SABA) and 3-month combined inhalation of long-acting β2-agonist (LABA) and corticosteroid among patients with these subgroups. RESULTS: Among the 130 COPD patients, 41 (31.5%) had normal DLCO and RV/TLC, 28 (21.5%) low DLCO and normal RV/TLC, 31 (23.8%) normal DLCO and high RV/TLC, and 30 (23.1%) low DLCO and high RV/TLC. The normal DLCO/high RV/TLC subgroup showed a signifi-cantly larger flow response (changes in forced expiratory volume in 1 s) to salbutamol than the normal DLCO/RV/TLC subgroups, and a larger volume response (changes in forced vital capacity) than the two normal RV/TLC subgroups. The normal DLCO/high RV/TLC subgroup also showed significantly larger flow and volume response to 3-month combined inhalation of LABA and corticosteroid than the two normal RV/TLC subgroups. CONCLUSION: COPD subgroups classified by DLCO and RV/TLC may have different pulmonary function responses to pharmacological treatment. © 2011 The Union. | * |
dc.language | English | * |
dc.title | Different therapeutic responses in chronic obstructive pulmonary disease subgroups | * |
dc.type | Article | * |
dc.relation.issue | 8 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1104 | * |
dc.relation.lastpage | 1110 | * |
dc.relation.journaltitle | International Journal of Tuberculosis and Lung Disease | * |
dc.identifier.doi | 10.5588/ijtld.10.0553 | * |
dc.identifier.wosid | WOS:000293678000017 | * |
dc.identifier.scopusid | 2-s2.0-79960426876 | * |
dc.author.google | Lee J.S. | * |
dc.author.google | Huh J.W. | * |
dc.author.google | Chae E.J. | * |
dc.author.google | Seo J.B. | * |
dc.author.google | Ra S.W. | * |
dc.author.google | Lee J.-H. | * |
dc.author.google | Kim E.-K. | * |
dc.author.google | Lee Y.K. | * |
dc.author.google | Kim T.-H. | * |
dc.author.google | Kim W.J. | * |
dc.author.google | Lee J.H. | * |
dc.author.google | Lee S.-M. | * |
dc.author.google | Lee S. | * |
dc.author.google | Lim S.Y. | * |
dc.author.google | Shin T.R. | * |
dc.author.google | Yoon H.I. | * |
dc.author.google | Sheen S.S. | * |
dc.author.google | Oh Y.-M. | * |
dc.author.google | Lee S.-D. | * |
dc.contributor.scopusid | 이진화(56646645800;58376333800) | * |
dc.date.modifydate | 20240419140935 | * |