View : 13 Download: 6

WHO classification of malignant lymphomas in Korea: Report of the third nationwide study

Title
WHO classification of malignant lymphomas in Korea: Report of the third nationwide study
Authors
Kim J.-M.Ko Y.-H.Lee S.-S.Huh J.Kang C.S.Kim C.W.Kang Y.K.Go J.H.Kim M.K.Kim W.-S.Kim Y.J.Kim H.-J.Kim H.K.Nam J.H.Moon H.B.Park C.-K.Park T.I.Oh Y.-H.Lee D.W.Lee J.S.Lee J.Lee H.Lim S.-C.Jang K.Y.Chang H.-K.Jeon Y.K.Jung H.R.Cho M.-S.Cha H.J.Choi S.J.Han J.H.Hong S.H.Kim I.
Ewha Authors
조민선
SCOPUS Author ID
조민선scopus
Issue Date
2011
Journal Title
Korean Journal of Pathology
ISSN
1738-1843JCR Link
Citation
vol. 45, no. 3, pp. 254 - 260
Indexed
SCOPUS WOS scopus
Abstract
Background: The aim of study was to determine the relative frequency of malignant lymphoma according to World Health Organization (WHO) classification in Korea. Methods: A total of 3,998 cases diagnosed at 31 institutes between 2005 and 2006 were enrolled. Information including age, gender, pathologic diagnosis, site of involvement and immunophenotypes were obtained. Results: The relative frequency of non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) was 95.4% and 4.6%, respectively. B-cell lymphomas accounted for 77.6% of all NHL, while T/natural killer (T/NK)-cell lymphomas accounted for 22.4%. The most frequent subtypes of NHL were diffuse large B-cell lymphoma (42.7%), extranodal marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (19.0%), NK/T-cell lymphoma (6.3%) and peripheral T-cell lymphoma (PTCL), unspecified (6.3%), in decreasing order. The relative frequency of HL was nodular sclerosis (47.4%), mixed cellularity (30.6%), and nodular lymphocyte predominant (12.1%) subtypes. Compared with a previous study in 1998, increase in gastric MZBCL and nodular sclerosis HL, and slight decrease of follicular lymphoma, PTCL, and NK/T-cell lymphoma were observed. Conclusions: Korea had lower rates of HL and follicular lymphoma, and higher rates of extranodal NHL, extranodal MZBCL, and NK/T-cell lymphoma of nasal type compared with Western countries. Changes in the relative frequency of lymphoma subtypes are likely ascribed to refined diagnostic criteria and a change in national health care policy.
DOI
10.4132/KoreanJPathol.2011.45.3.254
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
Files in This Item:
001.pdf(476.57 kB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE