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Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold

Title
Pre-wetting process with helium atmospheric pressure glow discharge for three-dimensional porous scaffold
Authors
Han I.Vagaska B.Lee D.H.Park B.J.Shin S.-W.Kim J.K.Lee S.J.Park J.-C.
Ewha Authors
이승진
SCOPUS Author ID
이승진scopus
Issue Date
2011
Journal Title
Macromolecular Research
ISSN
1598-5032JCR Link
Citation
vol. 19, no. 7, pp. 711 - 715
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
Recently, three-dimensional polymer scaffolds were developed for tissue regeneration. Conventional pre-wetting processes require a lengthy processing time and have residue problems. In this study, a helium atmospheric pressure glow discharge (He-APGD) was employed as a pre-wetting process for porous poly-(L-lactide-co-ε-caprolactone) (PLCL) scaffold. The three minutes treated PLCL scaffold absorbed the culture media and contained grafted hydroxyl, carbonyl, and carboxyl groups. Moreover, it did not show cytotoxicity, did not require residual rinsing steps and showed a homogeneous cell distribution. The He-APGD treatment has a short processing time and promotes a homogenous cell distribution. Therefore, this pre-wetting process is expected to find many applications in the future. © 2011 The Polymer Society of Korea and Springer Netherlands.
DOI
10.1007/s13233-011-0701-7
Appears in Collections:
약학대학 > 약학과 > Journal papers
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