Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 정성애 | * |
dc.date.accessioned | 2016-08-28T12:08:42Z | - |
dc.date.available | 2016-08-28T12:08:42Z | - |
dc.date.issued | 2011 | * |
dc.identifier.issn | 1078-0998 | * |
dc.identifier.other | OAK-7606 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221647 | - |
dc.description.abstract | Background: Distinguishing intestinal tuberculosis (ITB) from Crohn's disease (CD) is challenging. This study prospectively evaluated the clinical utility of the QuantiFERON-TB gold test (QFT) in the differential diagnosis of ITB and CD, and compared it with the clinical utility of the tuberculin skin test (TST). Methods: Patients with suspected ITB or CD on colonoscopic findings were enrolled from 13 hospitals in Korea between June 2007 and November 2008. A QFT and TST were performed. When the initial diagnosis was not confirmed, 2-3 months of empiric antituberculous therapy was administered. Results: In all, 128 patients were analyzed; 64 patients had ITB and 64 patients had CD. The median age of patients with ITB was greater than the patients with CD (47 years versus 31 years, P < 0.001). The positive rate for the QFT and TST (≥10 mm) in patients with ITB was significantly higher than patients with CD (67% versus 9% and 69% versus 16%, respectively; P < 0.001). The QFT and TST had good agreement (Î = 0.724, P < 0.001). The diagnostic validity of QFT in ITB had a 67% sensitivity, 90% specificity, 87% positive predictive value, and 73% negative predictive value. There was no difference in these parameters between the QFT and TST. The likelihood ratio for a positive QFT was higher than a positive TST in the diagnosis of ITB (7.1 and 4.4, respectively). Conclusions: The QFT is a limited but useful diagnostic aid in combination with the TST in the diagnosis of ITB. © 2010 Crohns & Colitis Foundation of America, Inc. | * |
dc.language | English | * |
dc.title | Prospective evaluation of the clinical utility of interferon-γ assay in the differential diagnosis of intestinal tuberculosis and Crohn's disease | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 17 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1308 | * |
dc.relation.lastpage | 1313 | * |
dc.relation.journaltitle | Inflammatory Bowel Diseases | * |
dc.identifier.doi | 10.1002/ibd.21490 | * |
dc.identifier.wosid | WOS:000290442400028 | * |
dc.identifier.scopusid | 2-s2.0-79955851324 | * |
dc.author.google | Kim B.J. | * |
dc.author.google | Choi Y.S. | * |
dc.author.google | Jang B.I. | * |
dc.author.google | Park Y.S. | * |
dc.author.google | Kim W.H. | * |
dc.author.google | Kim Y.S. | * |
dc.author.google | Jung S.-A. | * |
dc.author.google | Han D.S. | * |
dc.author.google | Kim J.S. | * |
dc.author.google | Choi J.H. | * |
dc.author.google | Choi C.H. | * |
dc.author.google | Jeen Y.T. | * |
dc.author.google | Cheon J.H. | * |
dc.author.google | Ye B.D. | * |
dc.author.google | Yang S.-K. | * |
dc.author.google | Kim Y.-H. | * |
dc.contributor.scopusid | 정성애(7403676915) | * |
dc.date.modifydate | 20240415140437 | * |