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Recent advances in the regioselective synthesis of Pyrazoles

Title
Recent advances in the regioselective synthesis of Pyrazoles
Authors
Yoon J.-Y.Lee S.-G.Shin H.
Ewha Authors
이상기
SCOPUS Author ID
이상기scopus
Issue Date
2011
Journal Title
Current Organic Chemistry
ISSN
1385-2728JCR Link
Citation
vol. 15, no. 5, pp. 657 - 674
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Pyrazole is the ubiquitous sub-structure of many natural products and biologically active compounds. In this respect, its regioselective synthesis drew a lot of attention from synthetic organic chemists, leading to the development of various regioselective modifications of the classical Knorr cyclocondensation reaction and alternative methods. This review covers the period of 2003 to the middle of 2009 on the regioselective synthesis of pyrazoles, which are categorized into four reaction types: (i) modified Knorr condensation reaction using 1,3-dicarbonyl surrogates; (ii) 1,3-dipolar cycloadditions approach; (iii) regioselective direct substitution reaction of the pyrazole ring system; and (iv) other methods. © 2011 Bentham Science Publishers Ltd.
DOI
10.2174/138527211794519005
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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