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Possible rheumatoid arthritis found in the human skeleton collected from the tomb of Joseon Dynasty, Korea, dating back to the 1700s AD

Title
Possible rheumatoid arthritis found in the human skeleton collected from the tomb of Joseon Dynasty, Korea, dating back to the 1700s AD
Authors
Kim D.K.Lee I.S.Kim W.-L.Lee J.S.Koh B.J.Kim M.J.Youn M.Y.Shin M.H.Kim Y.-S.Lee S.-S.Oh C.S.Shin D.H.
Ewha Authors
김이석
SCOPUS Author ID
김이석scopus
Issue Date
2011
Journal Title
International Journal of Osteoarchaeology
ISSN
1047-482XJCR Link
Citation
vol. 21, no. 2, pp. 136 - 149
Indexed
SSCI; AHCI; SCOPUS WOS scopus
Abstract
We report a possible rheumatoid arthritis (RA) case found in a Korean Joseon Dynasty (1392-1910) tomb encapsulated by a lime-soil mixture barrier (LSMB). The tomb is thought to have been constructed during the 1700s AD (1760 AD by carbon dating). In our anthropological examination, joint destruction, erosion or fusion (signs of polyarthritis) were identified mainly in the peripheral skeleton. Especially in both sides of the wrist bones, severe destruction/joint fusion possibly caused by polyarthritis was observed. A similar polyarthritis pattern also was seen in the right foot bones, even though we failed to confirm this symmetry due to the missing left foot bones. Despite these findings, signs suggestive of polyarthritis are very rarely seen in axial bones, even though bony fusions are found in the atlanto-occipital joint or thoracic vertebrae (TV) 9-10. By the osteological signs observed in this case, the individual, a female, might have been suffering from a very late stage of RA and died in her 40s, even though other forms of chronic arthritis could not be ruled out completely. Though the current case could not provide evidence to decisively settle the debates on the antiquity of RA, our report could be a stepping stone for forthcoming studies on RA cases found in East Asian countries. © 2009 John Wiley & Sons, Ltd.
DOI
10.1002/oa.1112
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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