Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경효 | * |
dc.date.accessioned | 2016-08-28T12:08:16Z | - |
dc.date.available | 2016-08-28T12:08:16Z | - |
dc.date.issued | 2011 | * |
dc.identifier.issn | 1011-8934 | * |
dc.identifier.other | OAK-7337 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221415 | - |
dc.description.abstract | To confirm the effect of 7-valent pneumococcal conjugate vaccine (PCV7), pneumococcal nasopharyngeal (NP) carriage was compared between vaccinated (3 + 1 doses PCV7) and non-vaccinated children. Vaccinated subjects were recruited from highly vaccinated regions (≥ 60%), Seoul and Incheon whereas control subjects were recruited from Jeju Island where vaccination rates are low (< 15%). NP swabs were obtained from 400 children aged 18-59 months. Serotype and antibiotic susceptibility was analyzed. Pneumococcal carriage rate was 18.0% (36/200) and 31.5% (63/200) for the vaccinated and control group, respectively. Among those vaccinated, 41.7% (15/36) of the serotypes were vaccine-related type (VRT: 6A, 6C, 19A) with the most common serotype 6C. The next common type was non-typable/non-capsule 30.6% (11/36) followed by non-vaccine type 16.7% (6/36) and vaccine type (VT) serotypes were found in only 11.1% (4/36). In contrast, 52.4% (33/63) of the isolates in the control group were VT. Resistance rates for penicillin and erythromycin were lower in the vaccine group (vaccine vs control; penicillin 45.2% vs 71.4%, erythromycin 74.2% vs 90.5%, P < 0.05). Multi-drug resistance was also lower in vaccinated subjects (vaccine vs control; 45.2% vs 69.8%, P < 0.05). PCV7 reduces carriage in VT which leads to replacement of pneumococci by antibiotic susceptible VRT or non-vaccine type strains. © 2011 The Korean Academy of Medical Sciences. | * |
dc.language | English | * |
dc.title | Nasopharyngeal pneumococcal carriage of children attending day care centers in Korea: Comparison between children immunized with 7-valent pneumococcal conjugate vaccine and non-immunized | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 26 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 184 | * |
dc.relation.lastpage | 190 | * |
dc.relation.journaltitle | Journal of Korean Medical Science | * |
dc.identifier.doi | 10.3346/jkms.2011.26.2.184 | * |
dc.identifier.wosid | WOS:000287468200004 | * |
dc.identifier.scopusid | 2-s2.0-79551658433 | * |
dc.author.google | Kim K.-H. | * |
dc.author.google | Hong J.Y. | * |
dc.author.google | Lee H. | * |
dc.author.google | Kwak G.Y. | * |
dc.author.google | Nam C.H. | * |
dc.author.google | Lee S.Y. | * |
dc.author.google | Oh E. | * |
dc.author.google | Yu J. | * |
dc.author.google | Nahm M.H. | * |
dc.author.google | Kang J.H. | * |
dc.contributor.scopusid | 김경효(35448653000) | * |
dc.date.modifydate | 20240301081003 | * |