View : 12 Download: 0

The origin of regenerating axons after end-to-side neurorrhaphy without donor nerve injury

Title
The origin of regenerating axons after end-to-side neurorrhaphy without donor nerve injury
Authors
Kim J.K.Chung M.S.Baek G.H.
Ewha Authors
김재광
SCOPUS Author ID
김재광scopus
Issue Date
2011
Journal Title
Journal of Plastic, Reconstructive and Aesthetic Surgery
ISSN
1748-6815JCR Link
Citation
vol. 64, no. 2, pp. 255 - 260
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The purpose of this study was to determine the origins of regenerated axons after end-to-side neurorrhaphy (ETSN) without donor nerve injury by comparing the time of appearance of regenerating axons for proximally coapted ETSN and distally coapted ETSN. Thirty rabbits were used in each group. In the proximal ETSN group, the ulnar nerve was transected and the distal end sutured to the median nerve 3 cm above the elbow joint, whereas in the distal ETSN group, it was 3 cm below the elbow joint. Coaptation was performed by wrapping the aponeurosis of nearby muscle. Observations were made weekly for 6 weeks after ETSN. Axonal regeneration was studied by morphometric analysis and immunohistochemistry. The times of appearance of regenerating axons differed in the proximal and distal ETSN groups. Axonal densities in proximal segments of donor nerves continuously increased and the axonal diameters of proximal segments of donor nerves continuously decreased with time after ETSN. Our findings suggest that regenerated axons after ETSN without donor nerve injury originate from the central nervous system rather than coaptation sites. © 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
DOI
10.1016/j.bjps.2010.04.033
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE