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Application of novel dynamic optical imaging for evaluation of peripheral tissue perfusion

Title
Application of novel dynamic optical imaging for evaluation of peripheral tissue perfusion
Authors
Kang Y.Lee J.Kwon K.Choi C.
Ewha Authors
권기환
SCOPUS Author ID
권기환scopus
Issue Date
2010
Journal Title
International Journal of Cardiology
ISSN
0167-5273JCR Link
Citation
vol. 145, no. 3, pp. e99 - e101
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Measurement of functional tissue perfusion should be needed for preventive measures, early diagnosis, and adequate treatment especially in the patients with peripheral vascular diseases (PVD). Significant attention has also been given to in vivo near-infrared (NIR) fluorescence imaging because of deep tissue penetration due to low absorbance and scattering. In this study, a new method, indocyanine green (ICG) perfusion imaging to evaluate the peripheral tissue perfusion that employs the intravenous injection of ICG dye, planar imaging with a CCD digital imaging system, and analysis of spatiotemporal dynamics have been applied to diagnose perfusion rate of human lower extremities from a normal and a PVD case. The feet tissue perfusions of the PVD patient were measured as 25% to 50% compared with those of normal feet tissue. The diagnostic result indicates that ICG perfusion imaging method is sensitive enough to diagnose PVD and take noninvasive monitoring treatment effects of peripheral vascular diseases in clinical setting. © 2008 Elsevier Ireland Ltd.
DOI
10.1016/j.ijcard.2008.12.166
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의학전문대학원 > 의학과 > Journal papers
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